Protein Info for AMB_RS14715 in Magnetospirillum magneticum AMB-1

Annotation: NAD(P)/FAD-dependent oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF07992: Pyr_redox_2
  • amino acids 2 to 287 (286 residues), 189.9 bits, E=1.4e-59
• PF00070: Pyr_redox
  • amino acids 144 to 215 (72 residues), 39.5 bits, E=1.3e-13

Best Hits

KEGG orthology group: None (inferred from 100% identity to mag:amb2923)

Predicted SEED Role

"Nitrite reductase [NAD(P)H] large subunit (EC 1.7.1.4)" in subsystem Nitrate and nitrite ammonification (EC 1.7.1.4)

MetaCyc Pathways

• alkylnitronates degradation (1/2 steps found)
• nitrate reduction V (assimilatory) (1/2 steps found)

KEGG Metabolic Maps

• Nitrogen metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.7.1.4

Use Curated BLAST to search for 1.7.1.4

Sequence Analysis Tools

See Q2W348 at UniProt or InterPro

Protein Sequence (421 amino acids)

>AMB_RS14715 NAD(P)/FAD-dependent oxidoreductase (Magnetospirillum magneticum AMB-1)
MHHLIVGAGPAGVTAAEIIRELEPGATITLVGDEPEPPYSRMAIPYMLVGKVGEDGTYLR
KGPNHYERLGITLMPGRRMSGLDPAARRIVLDGGETLAYDRLLLALGARPLRPDIEGLDL
PGIHTCWTLADARKIAAQAIPGSHVVLMGAGFVGTIVLEALALRQVSLTVVEMGDRMVPR
MMDETAGGMLKRWCEAKGVRVLTGTGIRRITQAQAAADTRDSLVVELSDGTSLPAHLVVV
SAGVRSNTEAVAASGIALGNGILVDDHMRTSLPDVFAAGDVAQGRDFMSGEAHVHAIQIT
AAAHGRIAAYNMTGNDQAYHGSLNMNVLDTLGLITCSFGSWQGNGGDCARLVDEAGFRYL
RLEFDGTSDVVIGAQAVGTTDHVGALRGLIQSKRRLGTAVKEQMMADPTRFMNGFVQILH
R