Protein Info for AMB_RS13735 in Magnetospirillum magneticum AMB-1

Annotation: Fe(2+) transporter permease subunit FeoB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 758 transmembrane" amino acids 285 to 304 (20 residues), see Phobius details amino acids 310 to 334 (25 residues), see Phobius details amino acids 338 to 371 (34 residues), see Phobius details amino acids 397 to 414 (18 residues), see Phobius details amino acids 426 to 452 (27 residues), see Phobius details amino acids 458 to 477 (20 residues), see Phobius details amino acids 515 to 536 (22 residues), see Phobius details amino acids 661 to 681 (21 residues), see Phobius details amino acids 690 to 712 (23 residues), see Phobius details amino acids 724 to 742 (19 residues), see Phobius details PF02421: FeoB_N" amino acids 4 to 161 (158 residues), 219.7 bits, see alignment E=3.6e-69 PF01926: MMR_HSR1" amino acids 5 to 118 (114 residues), 68.3 bits, see alignment E=1.6e-22 TIGR00437: ferrous iron transport protein B" amino acids 9 to 684 (676 residues), 630.5 bits, see alignment E=1.7e-193 PF17910: FeoB_Cyto" amino acids 180 to 265 (86 residues), 58.7 bits, see alignment E=1.6e-19 PF07670: Gate" amino acids 356 to 449 (94 residues), 87.9 bits, see alignment E=1.4e-28 amino acids 517 to 686 (170 residues), 68.1 bits, see alignment E=2.2e-22 PF07664: FeoB_C" amino acids 459 to 511 (53 residues), 75.5 bits, see alignment 5.3e-25

Best Hits

KEGG orthology group: K04759, ferrous iron transport protein B (inferred from 100% identity to mag:amb2731)

Predicted SEED Role

"Ferrous iron transport protein B" in subsystem Campylobacter Iron Metabolism or Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W3P0 at UniProt or InterPro

Protein Sequence (758 amino acids)

>AMB_RS13735 Fe(2+) transporter permease subunit FeoB (Magnetospirillum magneticum AMB-1)
MAHVVAVVGNPNCGKTTLFNVLTGSTQQVGNWPGVTVEKKVGTYLRDGQEYDLVDLPGIY
MIGGIAKGSEDERVSRDYILSGEPEVVVNIVDAYNLERNLYLTAQLLEMRVPLVVAVNMM
DLAEKSGIHIDVEALSRALDCPVVPLIASRKRGVDDLKAAIAAACQARHVPAVQPAHAQA
VAAARDALAPALAPAAAQRKVEAAWAALKLIEGDSFAEALAEGRLDDEVEAHRAAIEEHC
GEEADIIIADGRYTFIGEIMRGCVQQTHKVSLALTRRIDKVVLNRFLGVPVFLAAMYLMF
LFTIKVGGAFIEFFALAAEALVVDGSAAALAMVGAPEWVVAVVSGGIGGGIKTVASFIPI
IGSLFLFLSFLEDSGYMARAAFVMDRAMRSIGLPGKSFVPLIVGFGCNVPAIMATRTLES
RRDRVLTIMMAPFMSCGARLPVYALFAAAFFAESGQNVVFSLYLVGILFAVATGLILKST
LLRGEASTFVLELPPYHLPTARTVMMQAWQRLSEFIFRAGQFIVPLVTVLSVLNTLGTDL
SIGKENSKDSVLAAVSRAITPVFRPIGLSDENWPAAVGLFTGIFAKEAVVGTLNALYTQV
DAEDHGGDAQEAKPGIGDKLKAALATIPAKFSALVEAADEVKVKDGVFGAMVARFDGTAG
ALAYMVLILLYTPCVASLGAIRQEAGGGWTAFAVGWTSLLGYSASVACYQAATFARHPAQ
SLGWLTACVLAPLGAAGLMWLVARRRDGRLVTVSGVSP