Protein Info for AMB_RS13720 in Magnetospirillum magneticum AMB-1
Annotation: cation acetate symporter
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 66% identical to ACTP_ERWT9: Cation/acetate symporter ActP (actP) from Erwinia tasmaniensis (strain DSM 17950 / CIP 109463 / Et1/99)
KEGG orthology group: K14393, cation/acetate symporter (inferred from 100% identity to mag:amb2727)MetaCyc: 66% identical to acetate/glycolate:cation symporter (Escherichia coli K-12 substr. MG1655)
RXN0-1981; RXN0-5111; TRANS-RXN0-576
Predicted SEED Role
"Acetate permease ActP (cation/acetate symporter)" in subsystem Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q2W3P4 at UniProt or InterPro
Protein Sequence (561 amino acids)
>AMB_RS13720 cation acetate symporter (Magnetospirillum magneticum AMB-1) MKTTKTAIASALAFGGTALLASAALAAGADMGGAEKQATNWHAIIMFVIFVGMTLGITYW AAGRTKTAADFYAAGGGITGFQNGLAIAGDYMSAASFLGISALVYGSGYDGLIFSVGWLV GWPIILFLIAERLRNLGKYTFADVCGYRLARTPIRTFAATGSLIVVIFYLIGQMVGAGQL IKLLFGMDYIYAVMIVGALMMVYVTFGGMVATTWVQIIKACLLLGGATFIAFGVMSHFGF SFEKLFVKAIEVHPKKVAIMAPGALVTNPVDAISLGMALMFGTAGLPHILMRFFTVPDAR EARKSVFYATGFIGYFYILTFIIGFGAITLVATNPEYLTKGLGSLDLKGGNNMAAVWLAH AIGGDLFLGFISAVAFATILAVVSGLTLAGASAISHDLYASVIMHGQATEGREVTVSKIA SIGLGIIAVLLGLVFEKQNVAFIVALTFSVAASANFPVLVLSMFWGGLTTRGAVLGGMIG LLMSVIMVVLSKAVWVQSFGFKAEIFPFAYPALFSVPAAFFFSWLFSILDNSPQAQAERA AYEAQSIRSETGLGAEGAASH