Protein Info for AMB_RS13500 in Magnetospirillum magneticum AMB-1

Annotation: peroxiredoxin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF08534: Redoxin
  • amino acids 6 to 134 (129 residues), 70.6 bits, E=1.3e-23
• PF00578: AhpC-TSA
  • amino acids 6 to 132 (127 residues), 141.4 bits, E=1.4e-45

Best Hits

Swiss-Prot: 53% identical to BCP_COXBU: Putative peroxiredoxin bcp (bcp) from Coxiella burnetii (strain RSA 493 / Nine Mile phase I)

KEGG orthology group: K03564, peroxiredoxin Q/BCP [EC: 1.11.1.15] (inferred from 100% identity to mag:amb2684)

MetaCyc: 42% identical to thiol peroxidase (Escherichia coli K-12 substr. MG1655)
1.11.1.15-RXN [EC: 1.11.1.24]

Predicted SEED Role

"Thiol peroxidase, Bcp-type (EC 1.11.1.15)" in subsystem Thioredoxin-disulfide reductase (EC 1.11.1.15)

KEGG Metabolic Maps

• Glutathione metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.11.1.15

Use Curated BLAST to search for 1.11.1.15 or 1.11.1.24

Sequence Analysis Tools

See Q2W3T7 at UniProt or InterPro

Protein Sequence (153 amino acids)

>AMB_RS13500 peroxiredoxin (Magnetospirillum magneticum AMB-1)
MTTALGTPAPDFAMECDDGKTALADYKGKPLVLYFYPKDDTSGCTSEAKAFRDAMAEYQA
AGVEILGVSKDSVASHAKFRTKHELPFRLGSDPDGAVCEAYGVWKKKSMYGREYMGIERS
TFLIDKDGVLRAEWRKVKVTGHAEAVLKAAKGL