Protein Info for AMB_RS13135 in Magnetospirillum magneticum AMB-1

Annotation: tetratricopeptide repeat protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 659 PF07721: TPR_4" amino acids 5 to 30 (26 residues), 16.6 bits, see alignment (E = 6.6e-06) amino acids 112 to 135 (24 residues), 12.2 bits, see alignment (E = 0.00018) amino acids 212 to 236 (25 residues), 11.2 bits, see alignment (E = 0.00039) PF13428: TPR_14" amino acids 5 to 43 (39 residues), 26 bits, see alignment 7e-09 PF13424: TPR_12" amino acids 7 to 73 (67 residues), 44.3 bits, see alignment E=1.2e-14 PF13176: TPR_7" amino acids 8 to 38 (31 residues), 18.8 bits, see alignment (E = 9.2e-07) amino acids 44 to 75 (32 residues), 14.5 bits, see alignment (E = 2.1e-05) amino acids 112 to 141 (30 residues), 21.7 bits, see alignment (E = 1.1e-07) PF13174: TPR_6" amino acids 8 to 38 (31 residues), 19 bits, see alignment (E = 1.2e-06) PF13432: TPR_16" amino acids 9 to 62 (54 residues), 33.4 bits, see alignment 3.7e-11 amino acids 61 to 107 (47 residues), 19.4 bits, see alignment 8.6e-07 amino acids 115 to 177 (63 residues), 22.3 bits, see alignment E=1.1e-07 amino acids 184 to 233 (50 residues), 31.8 bits, see alignment 1.1e-10 PF13181: TPR_8" amino acids 76 to 108 (33 residues), 21 bits, see alignment (E = 1.9e-07) amino acids 111 to 141 (31 residues), 17.3 bits, see alignment (E = 2.9e-06) amino acids 180 to 211 (32 residues), 13.6 bits, see alignment (E = 4.4e-05) PF07719: TPR_2" amino acids 112 to 142 (31 residues), 25.6 bits, see alignment (E = 6.3e-09) PF14559: TPR_19" amino acids 121 to 177 (57 residues), 27.3 bits, see alignment 2.7e-09 PF13414: TPR_11" amino acids 190 to 225 (36 residues), 29 bits, see alignment 4.8e-10 PF13844: Glyco_transf_41" amino acids 291 to 438 (148 residues), 114.3 bits, see alignment E=3.4e-36 amino acids 460 to 620 (161 residues), 61.5 bits, see alignment E=3.5e-20

Best Hits

KEGG orthology group: None (inferred from 100% identity to mag:amb2610)

Predicted SEED Role

"TPR domain protein, putative component of TonB system" in subsystem Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W411 at UniProt or InterPro

Protein Sequence (659 amino acids)

>AMB_RS13135 tetratricopeptide repeat protein (Magnetospirillum magneticum AMB-1)
MTSDPALLLQQAEALHNQGRVDEAEALYHRVLRQAPQSPEAAKSLTNLGVIAHGRGRTGE
ALTLHGQALALAPQLAEAWCNRGDLLSDLGRLEEAEGDFVRACDLSPALLPAWFNLGNVR
LRRGDTAQAEPCYRRAAALAPHLPLIHAQLARCLDAMGQAEGAADAMEAAWRLAPDDWRL
LTDLGALQQQAGRLHAAQNSLRAAISLNPSHAAAHYNLGNVFYGEGRAAEAVACWQAAWS
MDPSLGEAASNALNGLHYLPDLTGDEVGRVHRRMMERDGSPPPAPHANAADPGRVIRVGY
VSADFRRHPLGQLMRPVLKGHDRSQVFAVCYATRPGHDEITAELRHHADLWREVAGLDDG
ALAQQVRQDGIDILVDLDGQTAGNRLGLFALRPAPVQMSWLGYPFTTGLAAMDYALLDRA
TVPPEAEAWFSETVLLLPGSRLCYQGPETPEPAPPPSLERGSVTFGSFNNIAKLNEQVIA
AWARILNRVPNSRLWLKWPHLALDEVASPLRQAFAAHGVDPGRLELRGNSPPAQLLAEYA
EIDIALDPFPYCGAFTSCEALWMGVPVVTLPGPRPFSRQTLALLAAMGLEDELARPDLAA
YEDLAVALAADPERLTRLRGGLRPLMRQGIGDAEAHVAGLERVFRQVWTDWCARIKGEA