Protein Info for AMB_RS13130 in Magnetospirillum magneticum AMB-1

Annotation: CoA transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02515: CoA_transf_3
  • amino acids 4 to 382 (379 residues), 438.1 bits, E=1.4e-135

Best Hits

KEGG orthology group: None (inferred from 100% identity to mag:amb2609)

MetaCyc: 60% identical to succinyl-CoA-glutarate CoA-transferase (Pseudomonas putida)
Succinate--hydroxymethylglutarate CoA-transferase. [EC: 2.8.3.13]

Predicted SEED Role

"L-carnitine dehydratase/bile acid-inducible protein F (EC 2.8.3.16)" (EC 2.8.3.16)

MetaCyc Pathways

• oxalate degradation II (1/3 steps found)
• L-lysine degradation X (3/6 steps found)
• L-lysine degradation IV (2/5 steps found)
• superpathway of L-lysine degradation (10/43 steps found)

Isozymes

Compare fitness of predicted isozymes for: 2.8.3.16

Use Curated BLAST to search for 2.8.3.13 or 2.8.3.16

Sequence Analysis Tools

See Q2W412 at UniProt or InterPro

Protein Sequence (406 amino acids)

>AMB_RS13130 CoA transferase (Magnetospirillum magneticum AMB-1)
MRALDDILVLDLSRVLAGPWCTQMLSDLGAKVIKVEKPGAGDDTRGWGPPFLTDPATEEK
GDAAYYLAANRGKHSVTIDMATPEGQELIRHLAAKADVLVENYKLGGLKKYGLDYDALKA
VNPRLVYCSITGFGQTGPYAPRAGYDFMIQAMGGMMSVTGEKDALPGGGPQKAGIAIADL
STGLHAVIAILAALNQRHRTGRGQYIDLGLLDVQVSMMSNQAQTYLVGGKAPARAGNGHA
AIVPYQAFPTQDGHLIIAVGNDGQFAKLAEVLGHPEWAADQRFILNRSRVEHREVLVPLL
EAETRRFPSAHLLDALERRQIPCGPINTMDKVFDDPQAQARNLRQEVPHALAGTVPTVAS
PLRLSDSPVIYDRGPPLLGEHTEVVLGDLLGLDAPAVEALRAKGVV