Protein Info for AMB_RS12645 in Magnetospirillum magneticum AMB-1

Annotation: protein translocase subunit SecD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 522 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 359 to 379 (21 residues), see Phobius details amino acids 386 to 406 (21 residues), see Phobius details amino acids 412 to 431 (20 residues), see Phobius details amino acids 452 to 476 (25 residues), see Phobius details amino acids 484 to 507 (24 residues), see Phobius details PF07549: Sec_GG" amino acids 41 to 62 (22 residues), 22.3 bits, see alignment (E = 1.8e-08) TIGR01129: protein-export membrane protein SecD" amino acids 45 to 507 (463 residues), 482.8 bits, see alignment E=9.1e-149 PF21760: SecD_1st" amino acids 148 to 207 (60 residues), 99.9 bits, see alignment E=1.1e-32 TIGR00916: protein-export membrane protein, SecD/SecF family" amino acids 271 to 500 (230 residues), 261.5 bits, see alignment E=7e-82 PF02355: SecD_SecF" amino acids 341 to 511 (171 residues), 59.4 bits, see alignment E=8.3e-20 PF03176: MMPL" amino acids 361 to 500 (140 residues), 26.3 bits, see alignment E=9.1e-10

Best Hits

Swiss-Prot: 46% identical to SECD_RICCN: Protein translocase subunit SecD (secD) from Rickettsia conorii (strain ATCC VR-613 / Malish 7)

KEGG orthology group: K03072, preprotein translocase subunit SecD (inferred from 100% identity to mag:amb2514)

Predicted SEED Role

"Protein-export membrane protein SecD (TC 3.A.5.1.1)" (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W4A7 at UniProt or InterPro

Protein Sequence (522 amino acids)

>AMB_RS12645 protein translocase subunit SecD (Magnetospirillum magneticum AMB-1)
MNHFPKWKIALVAIVSLFGIVFAVPNLLSRDQADRMPHWLQPVSLGLDLQGGSYLLLEVD
TAYVFREQLTSLVEGVRTTLRKEKIKYSDLGARGDQVSVRIIEADERAKAREFLRKIDAE
AAIETRDDGSMVLKYSEQAVKARKTAAIEQSLEIVRRRIDELGTREPSIQRQGEDRIVVQ
LPGVKDPDRIKALLGKTAKLTFHLLDDSTGADEAQKGRVPPGSMLLPSAEKERGMPESYV
VRKRIEVGGDMLVDSKATYSEGRPVVSFRFSAAGAKKFGDATRENAGKFLAIVLDEKVIS
APRINEPILGGSGIISGSFSVQQAQDLSLLLRAGALPAPLQVLEERTVGPDLGADSIQAG
AVASLLGLALVVVLMIIVYGSLGALADLAMVLNLILLLASLSALGATLTLPGIAGIVLTM
GMAVDANVLIYERMREEQRNGRSIMSAIQAGYDRAFGTIFDAHVTTLVAAALLFQFGSGP
VRGFAVTLTLGLLASLFTAVLVNRIMVVTWVRWRRLKTLPLA