Protein Info for AMB_RS12575 in Magnetospirillum magneticum AMB-1

Annotation: GGDEF domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 405 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details amino acids 59 to 80 (22 residues), see Phobius details amino acids 86 to 107 (22 residues), see Phobius details amino acids 119 to 137 (19 residues), see Phobius details amino acids 145 to 168 (24 residues), see Phobius details amino acids 175 to 194 (20 residues), see Phobius details amino acids 205 to 227 (23 residues), see Phobius details TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 232 to 390 (159 residues), 135.8 bits, see alignment E=5.8e-44 PF00990: GGDEF" amino acids 234 to 388 (155 residues), 126.1 bits, see alignment E=5.7e-41

Best Hits

Predicted SEED Role

"diguanylate cyclase (GGDEF domain) with PAS/PAC sensor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (405 amino acids)

>AMB_RS12575 GGDEF domain-containing protein (Magnetospirillum magneticum AMB-1)
MQSDLIDANSRGPKGWRSFAAHLFAPIKITWGQFFDLLVPIRHSAHIRRHAASVIISRIQ
LVAAIFAVMVPLWSIIDWFVFPWPQWAMMTALRLGSGVVFLLLAWPWDITKTRLQADSML
MAMLLVPPVFYLISIEVTADLNVTGIALLVTKLYALMPNIVLAGLAIFPLTAFEVALFSA
PAFAFAVIGLLMGGQTLTVDVHGPMFWLMVLVMGVAMFSGMSQLHYITALVNRAMIDPLT
GAYTRRSGGEALDLQFRLSAMRNTPLSIAFFDLDKFKSINDTFGHEEGDNALRALAENLR
QGLRRGDVLVRWGGEEFVAILTETNAEGARILMERLRSSGFGLRPDGNPMTASIGVAERL
ADNASDWPRLIELADQRMYEAKRGGRDRAVLPGGETLVFGEKPIF