Protein Info for AMB_RS12385 in Magnetospirillum magneticum AMB-1
Annotation: alanine--glyoxylate aminotransferase family protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 100% identity to mag:amb2464)Predicted SEED Role
"Serine--glyoxylate aminotransferase (EC 2.6.1.45)" in subsystem Photorespiration (oxidative C2 cycle) or Serine-glyoxylate cycle (EC 2.6.1.45)
MetaCyc Pathways
- photorespiration I (7/9 steps found)
- L-serine biosynthesis II (3/4 steps found)
- photorespiration III (6/9 steps found)
- photorespiration II (6/10 steps found)
- formaldehyde assimilation I (serine pathway) (8/13 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 2.6.1.45
Use Curated BLAST to search for 2.6.1.45
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q2W4F7 at UniProt or InterPro
Protein Sequence (400 amino acids)
>AMB_RS12385 alanine--glyoxylate aminotransferase family protein (Magnetospirillum magneticum AMB-1) MKYPTPPTVIPLDNILPDEPLLMMGAGPVPIPPKVAMANSLIINHLGDTMNAVIEQVKTM GRYVFQTNSPHVMGVAGPASAAMEMAIANLVEPGTRVLSICNGLFSRRLAEMADRVGGDV TRLDAPDKRAISAEDVEKALKTGRFQILTVVQGETSNTVWNRDLVEICRLGKQYGCLNIV DAVCTLSTMPMEMDEWMVDAIITGGQKGLSSIPGVSLIAFSEEAFARIEARNSPMAHWCL DARLAHQFWHNHSYHYTAPVSGILALHEALRLIGDETLPGRFRRHAQCSKALQNGVEAMG LKLLIAEDSRLNSVVGIELPEVISADQVRHIMSQVHKVEISGAFGLPIVRIGQMGEQSRA PNLFRTLHALGSAMRAAGGKVDMPGGMAELERSLASEVRG