Protein Info for AMB_RS11360 in Magnetospirillum magneticum AMB-1

Annotation: membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 457 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details TIGR01844: type I secretion outer membrane protein, TolC family" amino acids 24 to 432 (409 residues), 328.5 bits, see alignment E=3.3e-102 PF02321: OEP" amino acids 27 to 210 (184 residues), 109 bits, see alignment E=1.3e-35 amino acids 234 to 418 (185 residues), 98.4 bits, see alignment E=2.4e-32

Best Hits

KEGG orthology group: K12340, outer membrane channel protein TolC (inferred from 100% identity to mag:amb2245)

Predicted SEED Role

"Type I secretion outer membrane protein, TolC precursor" in subsystem Multidrug Resistance Efflux Pumps or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W526 at UniProt or InterPro

Protein Sequence (457 amino acids)

>AMB_RS11360 membrane protein (Magnetospirillum magneticum AMB-1)
MRKVSCRLIGAACMVVAASTPAMSETLEEVLASTYSSNPTLLARRAKLRSTDEGVPQALS
NWRPTVSLTGSVGRGSYDNNTLSPYSMSRTPRTQALTLSQPLFRGGRTLAATAQAENNVL
SERAQLAATEQTILLAAATAYLNVVRDDAVLKLSINNEQVLRRQYEATEERFKVGELTRT
DVSQAEARLAKATADRVAAEGNLQSSRANYVNNVGRPPEALVTPAQPPALPQSLDDVTST
ALAANPTVVSADFTHAAAKDGVDLVFGELLPTVSLSADISRNFETSTRENSSTAREVLLN
VSVPLYESGSVYSRVRASKHTAGQRRIEADQARRDAVETGTKSWETLQAARAQARSYQAQ
IKASELALAGVREESKVGSRTILDVLNAEQELFDARVNLVKAQRDVLAGAYQVKSALGQM
TAQGLNLPVAVYDPTKHYDDVRGQWFGNGIDKDKGYE