Protein Info for AMB_RS11240 in Magnetospirillum magneticum AMB-1

Annotation: cytochrome c oxidase subunit I

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 560 transmembrane" amino acids 27 to 49 (23 residues), see Phobius details amino acids 63 to 93 (31 residues), see Phobius details amino acids 105 to 123 (19 residues), see Phobius details amino acids 143 to 168 (26 residues), see Phobius details amino acids 180 to 209 (30 residues), see Phobius details amino acids 236 to 255 (20 residues), see Phobius details amino acids 266 to 284 (19 residues), see Phobius details amino acids 300 to 321 (22 residues), see Phobius details amino acids 343 to 367 (25 residues), see Phobius details amino acids 385 to 410 (26 residues), see Phobius details amino acids 424 to 447 (24 residues), see Phobius details amino acids 467 to 499 (33 residues), see Phobius details amino acids 526 to 548 (23 residues), see Phobius details PF00115: COX1" amino acids 25 to 461 (437 residues), 211.8 bits, see alignment E=8.5e-67

Best Hits

KEGG orthology group: K02274, cytochrome c oxidase subunit I [EC: 1.9.3.1] (inferred from 100% identity to mag:amb2222)

Predicted SEED Role

"Cytochrome c oxidase (B(O/a)3-type) chain I (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W549 at UniProt or InterPro

Protein Sequence (560 amino acids)

>AMB_RS11240 cytochrome c oxidase subunit I (Magnetospirillum magneticum AMB-1)
MVAKPVFRTCGFTGLKIHDEAEKLIKINAVTAIVVLALGGLFGLLVALTRWPTVHLLPAD
LFYLALTAHGIDILIVWCIFFEVALMYFASSILLQTRIATPKMGWVSYALMVLGAAITNW
KVLEGNSSVMMTSYVPMQADPLFYVGLILFAVGALIACFIFLGTLVVAKAEKTYEGSIPL
VTFGALVACIIAIYTIASGAIILIPTFLWSVGLISHIDPLMYKVVWWGMGHSSQQINVAA
HIAVWYAIAAILFGAKPLSEKVSRCAYLTYIFFLQIASAHHLLVEPGLSSAYKIFNTSYG
MYLAVLGSMIHGLTVPGCIEAAQRRKGFNNGMFEWLRKAPWGNPVFSGMFLSLILFGFLG
GISGVTMGVEQINIMIHNTIYVPGHFHATVAAGTTLAFMAITYFLVPVLFGRELILPGLA
KLQPYLFGLGMGVFSLFMMGAGTLGVSRRHWDMAFSDAPHAFAHAPAAFLMMGIVGVAAV
VAVVGGALFVLVIVGSVLFGKPVVHAPAAPAPAPSPVASYGNAEHVAVPGTFALALLFLT
VFVLYYFVNWKYLASTWIMS