Protein Info for AMB_RS11205 in Magnetospirillum magneticum AMB-1

Annotation: two-component sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 623 transmembrane" amino acids 17 to 39 (23 residues), see Phobius details amino acids 150 to 171 (22 residues), see Phobius details PF17149: CHASE5" amino acids 40 to 138 (99 residues), 27.5 bits, see alignment E=3.7e-10 PF08448: PAS_4" amino acids 275 to 383 (109 residues), 23.7 bits, see alignment E=7e-09 PF02518: HATPase_c" amino acids 512 to 622 (111 residues), 72.8 bits, see alignment E=4.6e-24

Best Hits

KEGG orthology group: None (inferred from 100% identity to mag:amb2213)

Predicted SEED Role

"Phytochrome, two-component sensor histidine kinase (EC 2.7.3.-); Cyanobacterial phytochrome B" (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W558 at UniProt or InterPro

Protein Sequence (623 amino acids)

>AMB_RS11205 two-component sensor histidine kinase (Magnetospirillum magneticum AMB-1)
MTFASALARRGSVAHRLIIRLGVTGLAVALLIAAGLVTADYQITLQRTDERFHQIEAGYL
ASVTENVWLQDGERLGQLVAGIRQTPYVQLVRVTDETGAVLVADGPGGDGEMITRRYPLA
RVYYGKELRIGLLEVSVSQRLLLRPVLHRAGLLLLANIILMAGILAALYWQVYRLIAQPL
AQMAAHVRHMNLDRADWEMQLVSPHDELKDLAAAYAEMRQAIDQGYHALRSREEHLRIVF
DNSPVSLWEEDFSRVKREVDALRGSMDLEIEVYLEAHPDFVVRCAALVEVVNVNAATLAL
HNAPSRAALLGNLQKTFTTASFHTFRRQIVAIWKGETELSVEGEVKTLSGDRRQVMLHWR
VPPGHEGCLDRVLVALENITERKAAEQALAASLEKLVRTNQELERLTEITAHDLQEPARG
IVSFSQLLERRIGPTLDADTSDLLGYLTNAGRRMQDQVRGLLAYAQVAPLDSPVEPQSLD
AALHGACEALADPIGQCGAVVEAEPLPRVMGNEALLIDLFIRLIDNALKFARAEAPPRIT
ITASVSDTMVTVAVADHGIGILPSYADDVFQVFRRLHGPDHFPGVGIGLAICRKIVERLG
GNIWIDTTVTEGCTVRFSLPPAP