Protein Info for AMB_RS11150 in Magnetospirillum magneticum AMB-1

Annotation: GGDEF domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 281 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 129 to 275 (147 residues), 42.3 bits, see alignment E=3.3e-15 PF00990: GGDEF" amino acids 140 to 275 (136 residues), 48.7 bits, see alignment E=3.8e-17

Best Hits

KEGG orthology group: None (inferred from 100% identity to mag:amb2203)

Predicted SEED Role

"GGDEF family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W568 at UniProt or InterPro

Protein Sequence (281 amino acids)

>AMB_RS11150 GGDEF domain-containing protein (Magnetospirillum magneticum AMB-1)
MQPRPGRKDVLAKFQTVPLTLCYHALKSHLPPGGRMPNQFRSEPVYAVGHVNEYALERDS
HPPGHHSHSPYPPNEPPHVPHSVADVASILGLPDAAVTPAVLKAVTGLLGEADRLRWMDS
QSRRRQAYLEGLAERDAVVPAFNRRGFIRELEGLLSTGHGSGTLVLLHVAGIESLRQSQG
LAAGDGALRHVTAHLVGALRSSDPVGLMGGSDFALLLSGTELPAARDKVRDIMERINQQP
FYWQGDVHAFALFSGYHVLQPGENAESAVAAADRARRGLPG