Protein Info for AMB_RS10875 in Magnetospirillum magneticum AMB-1

Annotation: HlyC/CorC family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 436 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details transmembrane" amino acids 23 to 24 (2 residues), see Phobius details amino acids 60 to 82 (23 residues), see Phobius details amino acids 94 to 119 (26 residues), see Phobius details amino acids 152 to 158 (7 residues), see Phobius details PF01595: CNNM" amino acids 9 to 201 (193 residues), 174.9 bits, see alignment E=2e-55 PF00571: CBS" amino acids 217 to 273 (57 residues), 22.8 bits, see alignment 1.4e-08 amino acids 288 to 335 (48 residues), 30.2 bits, see alignment 6.8e-11 PF03471: CorC_HlyC" amino acids 351 to 429 (79 residues), 64.4 bits, see alignment E=1.1e-21

Best Hits

Swiss-Prot: 45% identical to Y260_SYNY3: UPF0053 protein sll0260 (sll0260) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K03699, putative hemolysin (inferred from 100% identity to mag:amb2151)

Predicted SEED Role

"Magnesium and cobalt efflux protein CorC" in subsystem Copper homeostasis: copper tolerance or Phosphate metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W5C0 at UniProt or InterPro

Protein Sequence (436 amino acids)

>AMB_RS10875 HlyC/CorC family transporter (Magnetospirillum magneticum AMB-1)
MRLAFEIAVIIALVVLNGCFAMSELAIVSARRARLATLAAEGSKGARAALDLADNPTRFL
SSVQIGITLVGVLAGAYSGATLAEQLGAWIAAEFPVAASVAPGVAIALVVGAITYASLIV
GELVPKHIALANPEGIAERVARPMAMVARLTSPLIWLLEGSSHAVIRMLGIRRSDDHAVT
EEEVRAMIAEGTESGVFEPEEEEMISGVMRFGDRRIRGIMTPRANMVWIDLDWDADDILK
TLRDCPHSRLPVCRGGLDETLGVVQAKDLLNAAIDQRPVDVAAAVKVLAVVHDNAPALHV
LDVLKQSDIHMALVVDEYGSVEGIVTAADILGSILGTLSEHGEEYQGTITEREDGSWLMD
GDVAVDLAAERLGCRVMKEGGGDYTTAAGFILSQVRTIPSAGDHFIRDGWRFEVVDMDGR
RIDKILVSRETGTLGM