Protein Info for AMB_RS10810 in Magnetospirillum magneticum AMB-1
Annotation: benzoyl-CoA reductase subunit A
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 72% identical to BCRA_THAAR: Benzoyl-CoA reductase subunit A (bcrA) from Thauera aromatica
KEGG orthology group: K04114, benzoyl-CoA reductase subunit [EC: 1.3.7.8] (inferred from 100% identity to mag:amb2139)MetaCyc: 72% identical to benzoyl-CoA reductase alpha subunit (Thauera aromatica)
1.3.99.15-RXN [EC: 1.3.7.8]
Predicted SEED Role
"Benzoyl-CoA reductase subunit BadF (EC 1.3.99.15)" (EC 1.3.99.15)
MetaCyc Pathways
- benzoyl-CoA degradation II (anaerobic) (3/7 steps found)
- benzoyl-CoA degradation III (anaerobic) (2/9 steps found)
- benzoate fermentation (to acetate and cyclohexane carboxylate) (7/17 steps found)
- toluene degradation VI (anaerobic) (6/18 steps found)
- anaerobic aromatic compound degradation (Thauera aromatica) (11/27 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 1.3.7.8, 1.3.99.15
Use Curated BLAST to search for 1.3.7.8 or 1.3.99.15
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q2W5D2 at UniProt or InterPro
Protein Sequence (430 amino acids)
>AMB_RS10810 benzoyl-CoA reductase subunit A (Magnetospirillum magneticum AMB-1) MRCFIGIDLGSTTTKAVVMDENLQILGRGITNSRSNYDTAAAVSKQEALIDTRLTLFRRA LSNVPEVSGKVDDILSDLERNFRHVQFLEQLEDLQNTCIANIKGPRFAGREKVVIEALEG TFSRLRDSSAAQYAPGVKRKSDFFRDLAGAEFMSHGEAVCKEAGLGFDLILNVYDKSIIE VENRPPAGDMEGKFVRALEKGTMTGSSILAPVQSALAIPLEETYVVGTGYGRVRLPFPKE HIRSEILCHGLGAHMMYPDTRTVLDIGGQDTKGIQVDPVGIVENFQMNDRCAAGCGRYLG YIADEMNMGLHELGPLAMKSNKQVRINSTCTVFAGAELRDRLALGEKREDILAGLHRAII LRAMSILSRAGGVKDQFTFTGGVAKNEAAVRELRKLIKENYGDVTINIDPDSIYTGALGG ATFAVRAVVN