Protein Info for AMB_RS10680 in Magnetospirillum magneticum AMB-1

Annotation: monothiol glutaredoxin, Grx4 family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 109 TIGR00365: monothiol glutaredoxin, Grx4 family" amino acids 6 to 102 (97 residues), 151.4 bits, see alignment E=3.2e-49 PF00462: Glutaredoxin" amino acids 18 to 82 (65 residues), 74.1 bits, see alignment E=4.1e-25

Best Hits

Swiss-Prot: 50% identical to GLRX2_RICTY: Probable monothiol glutaredoxin 2 (grxC2) from Rickettsia typhi (strain ATCC VR-144 / Wilmington)

KEGG orthology group: K07390, monothiol glutaredoxin (inferred from 100% identity to mag:amb2117)

Predicted SEED Role

"Uncharacterized monothiol glutaredoxin ycf64-like" in subsystem Glutaredoxins or Glutathione: Redox cycle

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W5F4 at UniProt or InterPro

Protein Sequence (109 amino acids)

>AMB_RS10680 monothiol glutaredoxin, Grx4 family (Magnetospirillum magneticum AMB-1)
MNNPVFDRIRQDLSENDVVLYMKGTPMFPQCGFSAAVVQVLTNLGVKFKGIDILVDPSLR
DGIKQFTNWPTLPQLYVKGEFVGGCDIVREMAESGELKQLMTDKGVATA