Protein Info for AMB_RS10035 in Magnetospirillum magneticum AMB-1

Annotation: pyruvate:ferredoxin (flavodoxin) oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1193 TIGR02176: pyruvate:ferredoxin (flavodoxin) oxidoreductase" amino acids 1 to 1177 (1177 residues), 1748.7 bits, see alignment E=0 PF01855: POR_N" amino acids 13 to 243 (231 residues), 269.8 bits, see alignment E=1.6e-83 PF17147: PFOR_II" amino acids 265 to 347 (83 residues), 44.8 bits, see alignment 9.4e-15 PF01558: POR" amino acids 429 to 610 (182 residues), 111.8 bits, see alignment E=3e-35 PF10371: EKR" amino acids 629 to 681 (53 residues), 78.7 bits, see alignment (E = 1.6e-25) PF12837: Fer4_6" amino acids 684 to 707 (24 residues), 27.5 bits, see alignment (E = 1.6e-09) PF00037: Fer4" amino acids 685 to 708 (24 residues), 23.2 bits, see alignment (E = 3.2e-08) PF13237: Fer4_10" amino acids 687 to 759 (73 residues), 25 bits, see alignment 1e-08 PF12838: Fer4_7" amino acids 692 to 759 (68 residues), 37.2 bits, see alignment 2.4e-12 PF13187: Fer4_9" amino acids 692 to 760 (69 residues), 28.7 bits, see alignment 7.7e-10 PF13183: Fer4_8" amino acids 692 to 759 (68 residues), 28.6 bits, see alignment 1.2e-09 PF02775: TPP_enzyme_C" amino acids 966 to 1078 (113 residues), 31 bits, see alignment E=1.5e-10

Best Hits

KEGG orthology group: K03737, putative pyruvate-flavodoxin oxidoreductase [EC: 1.2.7.-] (inferred from 62% identity to atm:ANT_28320)

Predicted SEED Role

"Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-)" in subsystem Methionine Degradation or Pyruvate:ferredoxin oxidoreductase (EC 1.2.7.-)

Isozymes

Compare fitness of predicted isozymes for: 1.2.7.-

Use Curated BLAST to search for 1.2.7.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W5T1 at UniProt or InterPro

Protein Sequence (1193 amino acids)

>AMB_RS10035 pyruvate:ferredoxin (flavodoxin) oxidoreductase (Magnetospirillum magneticum AMB-1)
MITVDGNEACASVAYRVSEVAAIYPITPSSTMGELADQWASEGRKNIWGVIPDVAEMQHE
GGAAGAVHGALQAGSLATTFTASQGLLLMIPNMYKIAGELTSFCMHVTARTVATHGLSIF
GDHSDVMACRQTGFAMLASGSGQEAHDMAAIAHAATLKARVPFLHFFDGFRTSHEVTKIE
ELNDEDLLALLDADCIAAHRARALSPDHPTLRGTAQNPDTFFQMQEARNPWYDRCAGIVQ
EEMDQYAKLTGRAYKLFDYCGHPQAERVVIIMGSGAETVHETVTALVAKGEKVGVLKVRL
YRPFSIDAFVSALPTSVRSIAVLDRCKEPGSIGEPLYLDVLAGLAEAKAAGNRATAADPR
VIGGRYGLASKEFTPAMAKAVFDELAKDKPKAHFTVGITDDVTHLSLVPDESFKLDQPKV
KRAVFFGLGADGTVGANKNSIKIIAENAGFEGQGYFVYDSKKSGAITISHLRFSPEPIQS
AYLLDEADFVACHHFVFLDKYEVLRYAAPGATFLLNSPYPKDEVWNHLPREVQQEIIDKK
LQVHVIDARKVALATGMGNRINTIMQTCFFALSGVLPKDEAIGHIKKAIEKTYGRKSEKL
VAKNFEAVDETLHHLEEVAIPDTATSNRSLPPIVPEDSPDFVKRVSALMLSNHGDRLPVS
AFPVDGVWPTGTARFERRNIAAEIPVWDEGPCIQCNKCALVCPHAAIRAKVAEPADMADA
PASLKRMDWRSPEFKGSAYIIQVAPEDCTGCTLCVKVCPGKDKKDPSRLALRMESKDPIL
ETEKKNWAFFVDLPEVNKEKLGTPTVKTAQLLQPLFEFSGACLGCGETPYIKLMTQLWGD
RLMIANATGCSSIYGGNLPTTPYAQNAEGRGPAWANSLFEDNAEFGFGFRLAVDQHKNHA
KLLLAALTATGQVPEKLANEIAHAPQATEVEIAAQRLRILDLRKVLAGLKTAEARQLEQV
ADYLAEKVVWIVGGDGWAYDIGYGGLDHVFASGKNVNILVMDTEVYSNTGGQQSKATPIG
ASAKFAIAGKTLPKKDLGMMAMAYEDVYVANVAFGSKDVQTMRAFQDAVSYPGVSLIVAY
SHCIAHGYDLAHGLDQQKMAVEAGYWPLYRWDPRKMGTGESPLTLDSKEPNGKLYDFMKG
EARFQMVERADPERYRRLVESAETQLRRRFAMLRRFAGQPDVTPPSGGKEAAE