Protein Info for AMB_RS09930 in Magnetospirillum magneticum AMB-1

Annotation: hybrid sensor histidine kinase/response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 535 PF00072: Response_reg" amino acids 12 to 120 (109 residues), 67.3 bits, see alignment E=4e-22 PF00989: PAS" amino acids 140 to 250 (111 residues), 41.9 bits, see alignment E=2.7e-14 TIGR00229: PAS domain S-box protein" amino acids 142 to 258 (117 residues), 54.2 bits, see alignment E=8.2e-19 PF08448: PAS_4" amino acids 145 to 255 (111 residues), 51.2 bits, see alignment E=4e-17 PF13426: PAS_9" amino acids 148 to 252 (105 residues), 38.9 bits, see alignment E=2.8e-13 PF00512: HisKA" amino acids 306 to 371 (66 residues), 61.1 bits, see alignment E=2.6e-20 PF02518: HATPase_c" amino acids 420 to 529 (110 residues), 93.6 bits, see alignment E=3.2e-30

Best Hits

KEGG orthology group: None (inferred from 100% identity to mag:amb1968)

Predicted SEED Role

"FIG00779790: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W5V3 at UniProt or InterPro

Protein Sequence (535 amino acids)

>AMB_RS09930 hybrid sensor histidine kinase/response regulator (Magnetospirillum magneticum AMB-1)
MSASRTGPKENVLVVDDEPQILIAITDLLEDEFQVWTANDGPSALELLKEHEMAVILSDQ
RMPGMSGAEFLGQARVLSDATRVLVTGYSDLDALVSAVNLGQIHAYLSKPWNPLELRVVV
RTAADRWRLDRTLQQERTLMLALMNNIPDAVFIKDLQLKFSRVNQPQARLTGLADPSDLV
GQRLSELLESDHARTVEAEERAILDQGVGQLDRLESVTDQDGNALWYSVTKVPIRQGDEV
VGLAGIARDVTARKQAEDYLRRAHDELQQAVEERTRWLQKEISRRAQAEEQAQAAREAAE
AASRAKTIFLANMSHELRTPLNAIIGFSELANSIMGKADMDRYGGFLDNISESAHHLLRV
ISDILDVSRVEVGKVILRESVVDVAEAVRAAMRLVSHVVSNKRQSLTFSPQDGLPLIRAD
ERLMKQIVLNLLSNAAKFTPESGNIRVAANLVDGCVTVEVEDDGVGIAAEDIAMVLQPFG
QAENAISPKHEGTGLGLPLAKGFMELHGGSLTLESRVGEGTKVMLTFPASCVVTE