Protein Info for AMB_RS09915 in Magnetospirillum magneticum AMB-1

Annotation: hybrid sensor histidine kinase/response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 767 PF01627: Hpt" amino acids 7 to 96 (90 residues), 51.6 bits, see alignment E=1.8e-17 PF02518: HATPase_c" amino acids 352 to 491 (140 residues), 62.4 bits, see alignment E=1e-20 PF01584: CheW" amino acids 497 to 626 (130 residues), 51 bits, see alignment E=2.4e-17 PF00072: Response_reg" amino acids 651 to 763 (113 residues), 79.7 bits, see alignment E=3.8e-26

Best Hits

Predicted SEED Role

"Signal transduction histidine kinase CheA (EC 2.7.3.-)" in subsystem Bacterial Chemotaxis or Flagellar motility or Two-component regulatory systems in Campylobacter (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (767 amino acids)

>AMB_RS09915 hybrid sensor histidine kinase/response regulator (Magnetospirillum magneticum AMB-1)
MISIRERLLQAFQIEYREHVEAIRTLLDGLEHKAEGSGLAQLDEIFRRAHSLKGASRAVD
LPAVEEISHRMETLFAKVRSGQAKLDHDMAIGLGHVLDVIEDWVAANLANEPLPDTAATI
SALDAMIEGHAAPAVVAPPRAPPAPVPAPQLQSAPPVPQAPPDPPPAEPEDDEPADRAAT
TAPLRPEETVRVRALHLDRLLRSSNELLTETMNQRQVTQSLLGLDRSLGDFDRSWRRARK
NAAAALRDLGDYDRAIALERQYEALEQSLTGISRELRSVRRRQQRTGWALRQLGNDLQQE
VRQVRMVPAESIFGAFRKMVRDLARAVGKQVTVQVSGLDVEADRMVLQGLKDPVMHLLRN
ALSHGVEPPDERRAEGKSPAAHVSLSFDVSEGRLVVTIEDDGRGVNFEAIRRKAVERGLF
SEAQSFDVDRQSLIDVIFDPGFSTARVVDDLSGRGMGLSVVREAMAMMNGTVEVQDRKPM
GTCFRLSLPLTVSTQRLFLVECQGHVYGLPTEGVDRLYRVRAEDVGTVEGKSVVFLGDRQ
IPLLSLAHLLALGESAVKVTRNVVPLVVLKNGERRVAVAIDGFLSIREGLVKDIGVPGAR
GTMVAGGVLLEDGDIALVLNPFEIVETFRKSGSIRVLTTVEKPAEVKVPVILVVDDSLTT
RTLEKSILEAHGYQVRLAHDGLEALGRLRGESIDLIISDIQMPRLDGFGLLQAVKSDPAL
KSIPLILVSSLEAREDKERGLELGADAYVVKRKFDQKELLETIGQFL