Protein Info for AMB_RS09465 in Magnetospirillum magneticum AMB-1

Annotation: hybrid sensor histidine kinase/response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1218 PF01590: GAF" amino acids 148 to 277 (130 residues), 39.3 bits, see alignment E=4.2e-13 PF08447: PAS_3" amino acids 324 to 402 (79 residues), 37.7 bits, see alignment 9.2e-13 amino acids 454 to 530 (77 residues), 25.7 bits, see alignment 5.2e-09 TIGR00229: PAS domain S-box protein" amino acids 430 to 551 (122 residues), 27.5 bits, see alignment E=1.5e-10 amino acids 677 to 802 (126 residues), 63.9 bits, see alignment E=7.6e-22 PF13426: PAS_9" amino acids 570 to 666 (97 residues), 22.7 bits, see alignment E=4.3e-08 amino acids 692 to 796 (105 residues), 37.5 bits, see alignment E=1.1e-12 PF00989: PAS" amino acids 681 to 794 (114 residues), 27.6 bits, see alignment E=1.1e-09 PF13188: PAS_8" amino acids 681 to 736 (56 residues), 36.1 bits, see alignment 2e-12 PF08448: PAS_4" amino acids 702 to 799 (98 residues), 29.4 bits, see alignment E=3.7e-10 PF00512: HisKA" amino acids 820 to 882 (63 residues), 42.2 bits, see alignment 3e-14 PF02518: HATPase_c" amino acids 928 to 1077 (150 residues), 65.9 bits, see alignment E=2e-21 PF00072: Response_reg" amino acids 1100 to 1206 (107 residues), 61.9 bits, see alignment E=2.8e-20

Best Hits

KEGG orthology group: None (inferred from 100% identity to mag:amb1872)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W649 at UniProt or InterPro

Protein Sequence (1218 amino acids)

>AMB_RS09465 hybrid sensor histidine kinase/response regulator (Magnetospirillum magneticum AMB-1)
MKDTDSHPTKARRWRLPWHGAAVAADVPEMGDVPETGGGPAVAAADCLWSVDARGRLIAL
SAPLGVSLPLPWWRVVRLERTDRRALAISLKSGQPFSGLRASLRRGPLAGTGLDLSGRGR
HGGWSGAALVRDDPPLPDFGTDGRRGADLIQAVLEQTATALAVGTVFVARRERDGTLIPE
FAAADPAVGGDIVGHPYRSLGTACGDVLSTGRPLVVAAGLDERYPLLGRFRRLGVTAYAG
APLFDGSEAPGGVLVALGTSPFDDPSRVEAILAAAARCVAPHFRAALEERRLSHAAARFS
SLLDNLPGMAYRVRMSPDGRRRMLYASQGAERLIGITPAEMCRLPSDRLLELRHPDDRER
TLADTIDRLGRQDEVSLRWRLARPSGTVSWVRSSERLVGRDGADLLVEGLLQDCGAEVEV
EDELARRVRELKAVADYAPDWESWLDEDGGLRWLSPGVEKVTGYTVEECRALAGYPRSLV
CDEDLGVFDTAMAAAGAGSAVADIDIRIRRRWGEASWCSLSIQPVIADGHPAGLRLCIRR
IDRRKAAEQMLHQREEEIARVLAALDLVREAVIVSNAEGTISYANAAAARLLGFEAAAAL
RGHPWRTLGLAGSSSAPFLDIIESSLASRGAWSGELVLGQGEGAIYLDTRFARMPQDGFI
AVLTDIGARKLADEQLRENQERYRALFETAGDAIFLMEGAGIIDCNPRAEAVFGHGRGEL
QGHGLHDFAPPRQTDGRESKVVAAGLLAKALGGHPQAYEWLGRHKDGSLIHLDVTLTCVP
RRGRPYLVAVVRDVTERRRREDEQRHLEQQLAQARKLEALGQLAGGVAHDFNNILGAIRG
FADLLSDEVPAGSPGERYVRRILTASDRAKGVVRQILAFSRRSEVSHGTVDLGRLAEECL
GLLRASLPATTGLTFNHGAGAAGTVVDGDRDQLSQVILNLVINANDALDGVPGDIQVIVA
RSGDGAELRRLTSRTRPELALAVEVETDAGGGVTAFTGRFDPDRPHVTLSIIDSGPGIPQ
AVIAHAFDPFFTTKAARQGTGLGLAVVHSIVLAHHGAIVVRSHPDRGCRFDIVLPMGQGD
AAAEMAVSGTEAALPPGTRVLVVDDDADFGDMILAMLEHRGVEAAVVSSPLDALEVLRDH
PDAWDVMVTDQTMPGMRGIDLVKAVKAIRPDLPCLICTGYPEALDEAALTKAGVFALLHK
PVDFPHYFAQLARALAVD