Protein Info for AMB_RS09315 in Magnetospirillum magneticum AMB-1

Annotation: PAS domain S-box protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1500 1616 transmembrane" amino acids 58 to 81 (24 residues), see Phobius details amino acids 351 to 372 (22 residues), see Phobius details amino acids 384 to 405 (22 residues), see Phobius details PF08448: PAS_4" amino acids 500 to 612 (113 residues), 24.1 bits, see alignment 1.6e-08 TIGR00229: PAS domain S-box protein" amino acids 516 to 614 (99 residues), 33 bits, see alignment 2.9e-12 amino acids 627 to 743 (117 residues), 46.3 bits, see alignment 2.3e-16 amino acids 745 to 872 (128 residues), 29.3 bits, see alignment E=4e-11 PF08447: PAS_3" amino acids 520 to 600 (81 residues), 51.4 bits, see alignment 4.8e-17 amino acids 646 to 718 (73 residues), 28.4 bits, see alignment 7.2e-10 PF00989: PAS" amino acids 626 to 733 (108 residues), 23.4 bits, see alignment 2.2e-08 PF13426: PAS_9" amino acids 635 to 735 (101 residues), 41.2 bits, see alignment 7.6e-14 PF00512: HisKA" amino acids 885 to 950 (66 residues), 78.5 bits, see alignment (E = 1.5e-25) PF02518: HATPase_c" amino acids 997 to 1110 (114 residues), 93.1 bits, see alignment 6.9e-30 PF00072: Response_reg" amino acids 1132 to 1247 (116 residues), 61.9 bits, see alignment 2.9e-20 amino acids 1281 to 1392 (112 residues), 104 bits, see alignment 2.4e-33 PF01627: Hpt" amino acids 1458 to 1527 (70 residues), 41.9 bits, see alignment (E = 4.5e-14)

Best Hits

KEGG orthology group: K11527, two-component system, unclassified family, sensor histidine kinase and response regulator [EC: 2.7.13.3] (inferred from 100% identity to mag:amb1841)

Predicted SEED Role

No annotation

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W680 at UniProt or InterPro

Protein Sequence (1616 amino acids)

>AMB_RS09315 PAS domain S-box protein (Magnetospirillum magneticum AMB-1)
MNPGAPHITLSQGHTTDYLAGNEAGLMVRRWGCMTDQAPTPQRSEQPRAGRTSIRNSLLV
RAFFIVVIALGVFAASTYWLIVAPTIDRLADTQMRQTAGELEARVRRLLATVEITLNTSR
HWGMNGSLDLDQLQRFNEFFFPIIENHPEISSVILAHESGREILLLLTPDGKWVNRLSDP
DKRGKATTWITWSAGRVMEKTEVLERDYDARQRPWFKGALAMARDDDIHWTAPYIFFTTK
EPGITAASRWTAADGSRYVIGHDVKLLDLSHFTRQVKAGPNGMGMLLDDQGQLVGVPRMP
RFDSDDEIKKAVLKPLADQNLPALVEGWRLWNDLGRPDGSLNPMRIDGDVWFSHFSRMAI
GSNPIWLGVIAPRHDFIPVGREQIILLILLILASLAMAALVTLPMARRFAAPLEALAQES
IRIGRLDLARPVNVASDLGEIQELSAAQEAMREALLSSTTRLEEANTTLEARVLERTEEL
EHSKSTAEWSRQLMRDMADSLPCAAFRFEVAPSGDQSFRFISAKAEEIWGYTPDELINEP
DLRFWRIHPGDLAKAHQALEEALLEGSSTNQLYRVMNRHGEARWIETRAMASRLADGTRV
WNGYWLDVTEREEALAAMTGAMEEQSAIFQSAGLGIAVIRDRHIVRSNKSLAQLLGYGPS
ELDGQSTGVVFANEGDFERMGREAYPALAQGETFQGDWEYRRKNGTTFWGRTSGRAIDSG
DLSKGSVWVCDDITDRRNWEHRLQQAEERLRALTNSVPAAVFELRNEGEDFWFTFMGRQV
RGILGVGADQLLANAGRLYGTVRDGDRETLESVIEGALEQGVRFSTQYRLDAPGEERWVR
MEAVPIVAQAGGGTWAGFFQDVSAEKLAEAALTRAKELAEDATRMKSDFLANMSHEIRTP
MNAIIGMSHLALKTELTPRQHDYVKKIQSAGQHLLGIINDILDFSKIEAGKLAVEHTDFE
LDKVLDNIANLLTEKTRAKSLELVFDIPSEVPRTLVGDSLRLGQILINYANNAVKFTENG
EIDIIARVKERSETEVLLYFAVRDTGIGITAEQAARLFQSFEQADTSTTRKFGGTGLGLA
ISKRLAELMGGEVGVESEYGKGSTFWFTARMGIGTVRKRRLLPSPDLRGRRVLVVDDNDN
ARTVLADLMAGMTFQVTTRASGLEAVDEVKRAAMAGTPYEIVLLDWRMPGMDGIETAHHL
MALGLDPAPRLLMVTAYGREEVLNLITEAGIEDVLIKPVSASILFDTIMRLFGCQPAEPR
DVDGGHSSSEMHLETIRGARILLVEDNDLNQQVATELLGDAGFQVDVADDGAIALAKVRR
NAYDMVLMDMQMPVMDGVAATREIRRLGQFDHLPIVAMTANAMQRDRDRCLDAGMNDFIT
KPIDPDQLWAALLRWIAPRHSPAAAHGASAPSETGEEHSIPRIDGLDTTTGLRRVQGKTR
LYLTSLRKFAAGRKSVAGDIRAALEADDWSTAERLAHTTKGLAGMIGADEVQRRAADLEA
ALCDKLSRQEVEDLLDAMAAPLAALIAALDSTLPPEETIAPVAIDRAALDAACQRLLILL
AEDDAEADDVLEANAGLLQTAFPDHFPRIRAAIKDFNFDQALATLTEAVQRNRAPA