Protein Info for AMB_RS09305 in Magnetospirillum magneticum AMB-1

Annotation: two-component system response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 369 PF00072: Response_reg" amino acids 12 to 123 (112 residues), 90.7 bits, see alignment E=1e-29 PF01966: HD" amino acids 177 to 313 (137 residues), 55.9 bits, see alignment E=7.8e-19 PF13487: HD_5" amino acids 204 to 345 (142 residues), 110.7 bits, see alignment E=1.1e-35

Best Hits

Swiss-Prot: 52% identical to CDPD2_VIBCH: Probable cyclic di-GMP phosphodiesterase VC_1348 (VC_1348) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K07814, putative two-component system response regulator (inferred from 100% identity to mag:amb1839)

Predicted SEED Role

"Pole remodelling regulatory diguanylate cyclase" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W682 at UniProt or InterPro

Protein Sequence (369 amino acids)

>AMB_RS09305 two-component system response regulator (Magnetospirillum magneticum AMB-1)
MLPADFMDRATILVVDDSPDDVWLMSELLKADYRVKVANSGERGLKIAMGNERPDLVLLD
VMMPDIDGYEVCRQLKTDSRTHDIPVIFLTSKTRMAEEKRGLDMGAVDYITKPFSPSIVL
ARVKAHLRLKSSADFLRDQNRFLEREVAKRTKDVTAVKDVTILAMASLAETRDLMTGNHI
RRTQYYMSALATALQDHPRFAPLLDEAAITMLFKSAPLHDIGKIGIPDCILLKPGRLTPE
EFEVMKTHAALGRNAIESAERWLGTRLEFLTMAKEITHYHHERWDGDGYPEGLSGDDIPV
SARLMAVADVYDALISRRVYKEPIPHAEAVDIIIRDKGGRFDPDVVDAFVGIQDEFRAIA
RQYADRPTP