Protein Info for AMB_RS09180 in Magnetospirillum magneticum AMB-1

Annotation: peptidylprolyl isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 623 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details PF13624: SurA_N_3" amino acids 1 to 164 (164 residues), 138.6 bits, see alignment E=4.5e-44 PF13623: SurA_N_2" amino acids 3 to 139 (137 residues), 67.6 bits, see alignment E=2.8e-22 PF13145: Rotamase_2" amino acids 248 to 364 (117 residues), 101.2 bits, see alignment E=1.8e-32 PF00639: Rotamase" amino acids 306 to 350 (45 residues), 34.1 bits, see alignment 1.1e-11 PF13616: Rotamase_3" amino acids 309 to 351 (43 residues), 25.3 bits, see alignment 4.8e-09

Best Hits

KEGG orthology group: K03770, peptidyl-prolyl cis-trans isomerase D [EC: 5.2.1.8] (inferred from 100% identity to mag:amb1814)

Predicted SEED Role

"Peptidyl-prolyl cis-trans isomerase PpiD (EC 5.2.1.8)" (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W6A7 at UniProt or InterPro

Protein Sequence (623 amino acids)

>AMB_RS09180 peptidylprolyl isomerase (Magnetospirillum magneticum AMB-1)
MLDVFRTASKTWIVRLLFALLALSFVAWGAGDVVRGGVGRSPAIEIGRTSMSAAEVMGEF
KREVERLQPLFGGKLTAEDARKMGMLDRTIDSLIARTLIDEAARSLGLAATDETILRRVA
SNPAFKGPTGQFDRDLFRSRLSRLGHTEDSFMKTERTNMVRNQMVETVAAGIGAPQALTD
PLLAWREERRVAETFLIKDESTPLPAAPDAAVLEAYYKDNVSRFMAPEFRALTVLLLRPS
DVAGGIDIDEEMVRDAYRQRIEEFSTPERRAVSQIVFDESSAAAKATDLVTGGKDLATIA
KALNSEIIDLGVIEKNDLPEGLAEAVFKLSSGATSQPVKTALGWHVVKVSQIQPGRTRSF
DEVKAQLEQDMRKEKATDGLSELANRVEDALGGGATLEEAAKRHNLKTVKIAAVDAQGRG
ADGKPVADLPKSDQFLDVAFHTDQNTESPLTEVPNNGYFLLHVDGVTAPAPKPLAEIRSE
VVATWQAERRQEQARDKALKLADRIKVGEGIAQVALSAGAKLETSKPFVREPAEGTALPA
TIIAELFKAQPGGIATAPVQGGTLVARLAKVVTFDTNANPALTQAARQRVSQAVATDIAD
QYIAALNASIGVKVDRPQLTREE