Protein Info for AMB_RS07505 in Magnetospirillum magneticum AMB-1

Annotation: adenine deaminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01979: Amidohydro_1
  • amino acids 73 to 380 (308 residues), 47.1 bits, E=2e-16

Best Hits

Swiss-Prot: 47% identical to ENA_EUBBA: Enamidase (Ena) from Eubacterium barkeri

KEGG orthology group: None (inferred from 100% identity to mag:amb1486)

MetaCyc: 47% identical to enamidase subunit (Eubacterium barkeri)
Enamidase. [EC: 3.5.2.18]

Predicted SEED Role

"Enamidase (EC 3.5.2.18)" (EC 3.5.2.18)

MetaCyc Pathways

• nicotinate degradation III (2/9 steps found)
• superpathway of nicotinate degradation (2/18 steps found)

KEGG Metabolic Maps

• Nicotinate and nicotinamide metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.2.18

Sequence Analysis Tools

See Q2W785 at UniProt or InterPro

Protein Sequence (400 amino acids)

>AMB_RS07505 adenine deaminase (Magnetospirillum magneticum AMB-1)
MHTCSYTNNMREAPMSARLVIRNIGLLLSGDLHRPILDADSVLVEDGRIAAMGKAKDLDA
EGAKVVDCQGTTLAPGLIDSHVHPVFGDWTPRQNQIGWIDSFLHGGVTTMISAGEVHLPG
RPKDIVGVKALAITAQRAFANFRPGGVKVHAGAPVVEKGMVEEDFKELAAAGVTLLGEVG
LGGVKGAEEARQMVAWARKYGIRSTIHTGGPSIPGSGLIDQDVILEADADVIGHINGGHT
ALPDKQIACLCETCQRAIEIVHNGNQRSALVALRAAKELKQLERVILGTDSPAGSGVQPL
GILRMIAMLSSLGDVAPETAFCFATGNTARIHDLDVGLMEIGRAADFVIMDKAQHSAGTN
LLDSVRLGDLPGVSMTIIDGIIRTERSRNTPPATTVPVIL