Protein Info for AMB_RS06395 in Magnetospirillum magneticum AMB-1

Annotation: ATP-dependent helicase HrpB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 831 TIGR01970: ATP-dependent helicase HrpB" amino acids 4 to 830 (827 residues), 1045 bits, see alignment E=0 PF00270: DEAD" amino acids 9 to 166 (158 residues), 37.9 bits, see alignment E=2.3e-13 PF00271: Helicase_C" amino acids 205 to 330 (126 residues), 43.4 bits, see alignment E=5.6e-15 PF08482: HrpB_C" amino acids 687 to 818 (132 residues), 179.7 bits, see alignment E=4.8e-57

Best Hits

KEGG orthology group: K03579, ATP-dependent helicase HrpB [EC: 3.6.4.13] (inferred from 100% identity to mag:amb1260)

Predicted SEED Role

"FIG003033: Helicase domain protein"

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W7W1 at UniProt or InterPro

Protein Sequence (831 amino acids)

>AMB_RS06395 ATP-dependent helicase HrpB (Magnetospirillum magneticum AMB-1)
MHDLPIESVIPEIRAGLRQSHGLVLQAPPGAGKTTRVPLALLDEPWLAGQRILMLEPRRL
AARAAATRMASTLGEQPGETVGWRIRFDSRVGPKTRIEVVTEGILNRMIQDDPSLDGVGL
VIFDEFHERSLFADLGLALVLESRQGLRDDLKLVVMSATLDGEPVARLMGGAPVVTSQGR
AHPVETRFLARPEPRAFVDGVAAAVIRALDEEEGDILVFLPGSGEIRRVESLLADHPAAR
GVLIAPLYGDLSQDAQDGAIRPRRDGGRKVVLATAIAETSLTIEGVRVVVDGGRMRLARF
DPGSGMTRLVTLPVSRAGADQRRGRAGRLGPGVCYRLWSEADDRALLPFTAPEVTEADLA
PLALDLAQWGVTEALDLSWLDPPPAAHLAQARELLTELGALDDGLRITAHGKAMARLGLH
PRLAHMVLKGRDLRLGGLACDLAALLEERDVLRPGRDARDSDIRLRLDALRGRERGLPVD
KGGLARARQAARDGRRRLGLKAGEQEGDGRDAGLLLAFAYPDRLARRRPGGEPRYAMTGG
GGAVFASHEPLAAEEWLALAETDGDRREARIFLAAPLTLAEIEEHFGAQIRSETLCRWDG
REEVVQARARRVLWSLVIEDKPLKSAEPEALCAAMAEGVRQMGPACLPWTPDLERLCRRV
AFVRGLDPEGGWPDLSEAALLAGLEDWLVPYLSGITRRAHLARLDLAAALSGLLSWEQKK
RLDDLAPTHVEVPSGSRVPIDYSGEVPVLAVRLQEMFACAETPRIGGGKVALLLHLLSPA
RRPMQVTRDLASFWANTYKQVKADLKGQYPKHWWPDDPMQAEPTARIKPRK