Protein Info for AMB_RS04410 in Magnetospirillum magneticum AMB-1

Annotation: potassium transporter Kup

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 629 transmembrane" amino acids 12 to 34 (23 residues), see Phobius details amino acids 53 to 74 (22 residues), see Phobius details amino acids 106 to 129 (24 residues), see Phobius details amino acids 145 to 163 (19 residues), see Phobius details amino acids 175 to 193 (19 residues), see Phobius details amino acids 218 to 239 (22 residues), see Phobius details amino acids 251 to 274 (24 residues), see Phobius details amino acids 291 to 316 (26 residues), see Phobius details amino acids 343 to 363 (21 residues), see Phobius details amino acids 370 to 396 (27 residues), see Phobius details amino acids 403 to 423 (21 residues), see Phobius details amino acids 429 to 446 (18 residues), see Phobius details PF02705: K_trans" amino acids 16 to 469 (454 residues), 636.7 bits, see alignment E=1.8e-195 PF22776: K_trans_C" amino acids 479 to 629 (151 residues), 161.7 bits, see alignment E=1.2e-51

Best Hits

Swiss-Prot: 100% identical to KUP2_MAGSA: Probable potassium transport system protein kup 2 (kup2) from Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)

KEGG orthology group: K03549, KUP system potassium uptake protein (inferred from 100% identity to mag:amb0866)

MetaCyc: 53% identical to K+:H+ symporter Kup (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-3

Predicted SEED Role

"Kup system potassium uptake protein" in subsystem Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W905 at UniProt or InterPro

Protein Sequence (629 amino acids)

>AMB_RS04410 potassium transporter Kup (Magnetospirillum magneticum AMB-1)
MTAHGGDGKSRNVAGLMLAAIGVVFGDIGTSPLYAMKETFSGPHAVAMDKGNILGVLSLV
FWAITIIVSFKYVIIIMRADNRGEGGSLALLALVSHAAESNRRLSLMVSALGIFAAALFY
GDSIITPAISVLSAVEGLQVAAPHLEQWVVPLTIVILFVLFAIQSHGTDLVGKMFGPVML
VWFLTLAILGIRNLSHAPSVLAALSPHYAISFLFREGWHAFLALGSVVLAVTGAEALYTD
MGHFGRLPIRLAWYLLVLPALILNYFGQGALLIYNPEAIANPFFNLAPASLALPLVILAT
LATVIASQAVISGAFSVTRQAIQLGFLPRMEIIHTSEEEMGQIYLPFVNWLLMCMVMVLV
VGFKTSSNLAAAYGVAVTGTMVIDALLVGTVMLLIWKWNPRKVKWLIGGFLVVDLAFFLA
NSIKIPDGGWFPLVVGGLLFTILTTWKDGRKRLLARLKADALPVEDFLASLSDRVPRVPG
TAVFLTGTSEGVPIALLHNMKHNKIVHERVVLLTVIVEEVPFVPEERRLENRLLAPNFHR
VFLRYGFMESPNIPKALAHARTDQLGFFYEPMSVSYFVSRETLLPTEKPGLRGLRDTLFA
TLARMATSAMDFFHLPSNRVVELGSQIEI