Protein Info for AMB_RS03435 in Magnetospirillum magneticum AMB-1

Annotation: PAS domain-containing sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 586 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details TIGR00229: PAS domain S-box protein" amino acids 201 to 329 (129 residues), 51.7 bits, see alignment E=4.9e-18 PF08447: PAS_3" amino acids 228 to 315 (88 residues), 76.1 bits, see alignment E=4.4e-25 PF08448: PAS_4" amino acids 229 to 324 (96 residues), 35.2 bits, see alignment E=2.6e-12 PF00512: HisKA" amino acids 361 to 427 (67 residues), 64.1 bits, see alignment E=2e-21 PF02518: HATPase_c" amino acids 476 to 585 (110 residues), 96.3 bits, see alignment E=3.1e-31

Best Hits

KEGG orthology group: None (inferred from 100% identity to mag:amb0667)

Predicted SEED Role

"Two-component sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W9K4 at UniProt or InterPro

Protein Sequence (586 amino acids)

>AMB_RS03435 PAS domain-containing sensor histidine kinase (Magnetospirillum magneticum AMB-1)
MRPSMAEASALIWASMRARRAGRASNSSRSTSTAVNCFSQNVPGNRAALSDGGPLEGAQD
SFRDRDEGGRSAQPRKASPAPISSMSRRRSVVMTVPPVPAMIGRRSPCDNCGSAGQGLHP
GRILPFGHLVWPGGHAYLYLMRGMLEVGLPVRTPRGIGPGRESLRDETPARLRARVKALE
IAQREAQRTQRVLLATTRALRESEERYALAMRGPNEGLWDWNPITKELYLSARLLSILGF
ESDTLRTTSHEWLELVHPEDRDRYQATLVRHLKGEDAHFECEYRVTDRDGRWRWVLARGL
AVLDADGVATRMVGSIGDVTERHAYQRALQEANEQLEQRVVERTRELDLARCQAEEANRC
KSEFLANMSHELRTPLNAIIGFSDVMRSGVFGPVGNARYGEYIGWIWDSGHHLLRIINDI
LDLAKVEVGRFDLSRESTPVLPLLESAIRLVSERATRAEVNVGCKAEPGLGDAMLDPLRM
KQVLLNLLSNAVKFTPAGGSVSLEARHEGTDLVLIVADTGIGMDEESLEKALQPFVQVES
SLSRRYAGTGLGLPLAKSFSELHGGSLDLVSRPGEGTTVTVRIPRK