Protein Info for AMB_RS03220 in Magnetospirillum magneticum AMB-1

Annotation: two-component sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 844 signal peptide" amino acids 1 to 39 (39 residues), see Phobius details transmembrane" amino acids 54 to 72 (19 residues), see Phobius details PF12860: PAS_7" amino acids 350 to 463 (114 residues), 39.8 bits, see alignment E=1.4e-13 amino acids 479 to 595 (117 residues), 44.6 bits, see alignment E=4.3e-15 PF00512: HisKA" amino acids 612 to 679 (68 residues), 54.2 bits, see alignment E=3.8e-18 PF02518: HATPase_c" amino acids 726 to 839 (114 residues), 90.1 bits, see alignment E=4.1e-29

Best Hits

KEGG orthology group: None (inferred from 100% identity to mag:amb0625)

Predicted SEED Role

"FIG056333: sensor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W9P6 at UniProt or InterPro

Protein Sequence (844 amino acids)

>AMB_RS03220 two-component sensor histidine kinase (Magnetospirillum magneticum AMB-1)
MSFAPRIGTLGPLWGDDGMRAAFAAGLALMLAAGGAAAEEAPALASLRFDPLSLGIGALL
VLVPALAVLALLRWRMVSLAADAGRAVILADRLTESLLAAPDGFYAWLGEREICSRRLAV
LLGLFGGTESAFMDVLESFAAADAAQLDSAARRLREEGQGFELELRLRDGGRRVRAVGVR
ACGPEGAALADLVWMHDVTEGAAFEAELASRLAGLVVERERIEGLLGVLPIPAWVRDDDL
SLLHVNRAYARAVDVASPLAAVAGQIELASDGSVREARALAARARAAGEPRSESFHLVLG
GQRRFTEITEAPFEAEDGGLLTAGYALDLTRVEELQQELARHASAHAQVLEHLATAIAIF
STDTRLTFFNTAFTRLWRLEAEWLAAQPTYGAVLDSLRERRLLPEVADYRAYKEDELKRF
ISLIDAAETLLHLPDGRTLRRMIAAHPYGGLIFTYEDVTDTLALERSFNTALAVQRETLD
HLHEGVAVFKGDGRLRLFNPAYARIWNLAPSMLESEPHLNELVEAHRPYFEGGAERASVW
PEMRERLMALFNTRAPQSGRVERLDDSIVDFASVPLPDGAMLLTWLDVTDSARVERALRE
RNEALAAADLLKSEFIANVSAEVRKPLTTVIGFSEMLAAEYFGKLNKRQHEYARGITEAG
QGLQALISDILDLAAIEAGQMALELDTVDVHPMLSGVLGLVRERVREKKVTLDFDCPLDI
GWIVADERRLRQVLFNLLGNALKRTPSGGKVSVRAERRPSELALTISDTGTGLSDEQRER
LFGGFATGGRREALPAGRADDDSGIGLALVQRFVDLHGGRVELASAPGEGTVVTVRLPVG
SGAT