Protein Info for AMB_RS02935 in Magnetospirillum magneticum AMB-1

Annotation: PAS domain-containing sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 755 transmembrane" amino acids 39 to 60 (22 residues), see Phobius details amino acids 302 to 323 (22 residues), see Phobius details PF00672: HAMP" amino acids 327 to 374 (48 residues), 30.4 bits, see alignment 1.6e-10 TIGR00229: PAS domain S-box protein" amino acids 382 to 506 (125 residues), 100.2 bits, see alignment E=4.7e-33 PF13188: PAS_8" amino acids 386 to 437 (52 residues), 29.9 bits, see alignment 1.5e-10 PF00989: PAS" amino acids 386 to 496 (111 residues), 56.1 bits, see alignment E=1.4e-18 PF08448: PAS_4" amino acids 392 to 501 (110 residues), 41 bits, see alignment E=8e-14 PF13426: PAS_9" amino acids 397 to 497 (101 residues), 46.4 bits, see alignment E=1.6e-15 PF08447: PAS_3" amino acids 408 to 493 (86 residues), 52.6 bits, see alignment E=1.8e-17 PF00512: HisKA" amino acids 519 to 587 (69 residues), 67.4 bits, see alignment E=3.7e-22 PF02518: HATPase_c" amino acids 634 to 745 (112 residues), 98.8 bits, see alignment E=1.1e-31

Best Hits

KEGG orthology group: None (inferred from 100% identity to mag:amb0567)

Predicted SEED Role

"Signal transduction histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W9V4 at UniProt or InterPro

Protein Sequence (755 amino acids)

>AMB_RS02935 PAS domain-containing sensor histidine kinase (Magnetospirillum magneticum AMB-1)
MDCRHPVIGYGPLWGGKQDRMAEGGNRTLTWLGGARGHLFQVVVLGLVPAVFLGTLAIII
QLAESLSLQAAGSQVETLARMAAAIHDRGLESSREALAALATDPEDDECGSHYRHFLLAV
EGHYGFLRTDPSGRAGCSIAQGTDISWLTKGPQIGRAMETGAFATGPYVQLEDGRVALPM
AYPILDWLGTPRGVVATARSLDHLAKAVAPPILPDGARLLVLKSDGTVLARVPALSGDAP
AITPVPELREAAARGRGGSFTAIAITGETSVFGVAPLGRMAPETMVAVTMPVEMLGGSER
QFLRMAVTAFGIAGSGAVLLLWYSSRRLLFQPLGRLAGAMRRVRAGDMAARAGGGIGEVG
EMGDTFDTMVGALNEREARLTESEDRFRATFEQAAVGMCHTTLDRRFIRINSRFAEMLGC
APQELIGRSASDFTHPDDRKLGLDGIDHIIQGTRESNSIEKRYLRKDGTIVWANLTVSAL
RRDGQVEYIIGVAEDISWRKRAEDELRAAKEQAESASRAKSDFLAGMSHELRTPLNAIIG
FAETMYSQVLGPMPERYREYAGDISASGRHLLGIITDILDLAKIEAGRMELDDRPMEIAP
VVDVALRLLRDRGAAAGLNLISDLPPGLPQVMADERRIRQVVINLLANAVKFTPFGGRVT
VSASLTPDGGLELHVSDTGIGMTEEEAAQVIEPFVQVDARIARRHEGTGLGLPMVAAIME
MHGGAIAIASQPDAGTRVTVTFPPRRIFAVTATGR