Protein Info for AMB_RS02570 in Magnetospirillum magneticum AMB-1

Annotation: sigma-54-dependent Fis family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 457 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF00158: Sigma54_activat" amino acids 119 to 285 (167 residues), 242.5 bits, see alignment E=5e-76 PF14532: Sigma54_activ_2" amino acids 134 to 290 (157 residues), 71.3 bits, see alignment E=2.5e-23 PF07728: AAA_5" amino acids 143 to 263 (121 residues), 32.1 bits, see alignment E=2.7e-11 PF00004: AAA" amino acids 143 to 263 (121 residues), 21.7 bits, see alignment E=6e-08 PF02954: HTH_8" amino acids 397 to 437 (41 residues), 56.6 bits, see alignment 4.4e-19

Best Hits

Swiss-Prot: 66% identical to FLBD_CAUVC: Transcriptional regulatory protein FlbD (flbD) from Caulobacter vibrioides (strain ATCC 19089 / CB15)

KEGG orthology group: None (inferred from 100% identity to mag:amb0499)

Predicted SEED Role

"Response regulator of zinc sigma-54-dependent two-component system" in subsystem Zinc resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2WA22 at UniProt or InterPro

Protein Sequence (457 amino acids)

>AMB_RS02570 sigma-54-dependent Fis family transcriptional regulator (Magnetospirillum magneticum AMB-1)
MRLLIIGTLDGQIGAASQIAMARGAKVRQAEDVPAGLEVLRAQGADLVMIDVKRDIKGLI
DSLEAERIIVPVVACGIASDASAAVRAIKAGAKEYIPLPPDAELIAAVIAAVTQENHNII
FKDPRMGQTLKLAEQVANSDASIMITGESGTGKELIARFIHNKSKRSDKRFVAVNCAAIP
ENLLESELFGHEKGAFTGAVARRIGKFEEAQGGTLLLDEISEMDVRLQSKLLRAIQEKEI
DRVGGNQPVKVDVRILATSNRTMEDEVRKGTFREDLYYRLNVVTLALPALRERPLDIAVL
AEHFVKRYTEANGLPTRQLSAEARQLLSRHHWRGNVRELENTMHRAVLLASGAEIGPEAM
ILSGNPVGTNPDPMVAQAANAAASVIGARGGMVGKTVAEVERDLIIDTLSHCLGNRTHAA
NILGISIRTLRNKLKQYSDEGIDVPPPAGGEIERAMI