Protein Info for AMB_RS02235 in Magnetospirillum magneticum AMB-1

Annotation: methyltransferase domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 319 PF12840: HTH_20" amino acids 12 to 58 (47 residues), 38.6 bits, see alignment 5.1e-13 PF12802: MarR_2" amino acids 14 to 59 (46 residues), 37.2 bits, see alignment 1.5e-12 PF01022: HTH_5" amino acids 14 to 58 (45 residues), 55.6 bits, see alignment 2.3e-18 PF13412: HTH_24" amino acids 15 to 57 (43 residues), 24 bits, see alignment 1.4e-08 PF00891: Methyltransf_2" amino acids 130 to 253 (124 residues), 31.6 bits, see alignment E=6.5e-11 PF05175: MTS" amino acids 138 to 251 (114 residues), 24.4 bits, see alignment E=1.2e-08 PF01209: Ubie_methyltran" amino acids 139 to 254 (116 residues), 42.1 bits, see alignment E=4.2e-14 PF13489: Methyltransf_23" amino acids 146 to 261 (116 residues), 46.6 bits, see alignment E=1.8e-15 PF13847: Methyltransf_31" amino acids 152 to 253 (102 residues), 71.7 bits, see alignment E=3.5e-23 PF13649: Methyltransf_25" amino acids 153 to 245 (93 residues), 71.2 bits, see alignment E=5.8e-23 PF08241: Methyltransf_11" amino acids 153 to 248 (96 residues), 83.9 bits, see alignment E=6.1e-27 PF08242: Methyltransf_12" amino acids 153 to 247 (95 residues), 54.6 bits, see alignment E=9.3e-18

Best Hits

KEGG orthology group: K03892, ArsR family transcriptional regulator (inferred from 100% identity to mag:amb0432)

Predicted SEED Role

"Transcriptional regulator, ArsR family / Methyltransferase fusion"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2WA89 at UniProt or InterPro

Protein Sequence (319 amino acids)

>AMB_RS02235 methyltransferase domain-containing protein (Magnetospirillum magneticum AMB-1)
METLLTGLRAAAEPTRLRLLHLLAQGELTVTEITQILGQSQPRVSRHLKLMCEAGLLDRF
PEGAWVFYRLAAKGRGGAVARRLLDLLPGDDQTLTLDGQRLASIRAGRADKAQAYFRDNA
SRWNEIRSLQVDGAEVEKALLAVFAGRRIHDLVDMGTGTGRVLEVLGPHVERAIGIDLSR
EMLSVARTNLERLSLSNCMVRQGDIAQMPLPAATADAVTIHQVLHYATDPAALVAEAARV
LEPGGRLAVVDFAPHGEESLRDQHAHRRLGFEDAEVEGWLRAAGLEPGPVTRLPGEPLTV
VVWTAQKPFPDSKSTGATR