Protein Info for AMB_RS01470 in Magnetospirillum magneticum AMB-1

Annotation: two-component sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 469 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 38 to 56 (19 residues), see Phobius details PF00989: PAS" amino acids 120 to 153 (34 residues), 23.5 bits, see alignment 1.2e-08 PF08448: PAS_4" amino acids 122 to 200 (79 residues), 25.3 bits, see alignment E=3.8e-09 PF00512: HisKA" amino acids 231 to 295 (65 residues), 67.2 bits, see alignment E=2.7e-22 PF02518: HATPase_c" amino acids 344 to 467 (124 residues), 93.7 bits, see alignment E=2.5e-30

Best Hits

KEGG orthology group: K07636, two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC: 2.7.13.3] (inferred from 100% identity to mag:amb0290)

Predicted SEED Role

"Phosphate regulon sensor protein PhoR (SphS) (EC 2.7.13.3)" in subsystem High affinity phosphate transporter and control of PHO regulon or Phosphate metabolism (EC 2.7.13.3)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2WAN1 at UniProt or InterPro

Protein Sequence (469 amino acids)

>AMB_RS01470 two-component sensor histidine kinase (Magnetospirillum magneticum AMB-1)
MVIRGTVTGGRVLLFALFLSSPTAIMLVVLAGAGRLDVWPAIGTWVMVTSLLLPLVRSHL
GELSGLANWVRTLAHGGDIATAPAKDGMALAEIAAAVAALRRLWQHRSAELAETARWNAS
LLENLPDPLLLLDSSRRVVRANRAATRLFGRDPAGGDLAAVLRDPQVTEAVQAVLSGAAP
SRECEFSQAIPVERTFAARIDRLDGQPAFEAAIALLTLHELTAIRAMERMRADFVANASH
ELRTPLAALSGFIETLQGPARDDEEAREKFLGIMAEQSGRMSRLVADLLSLSRIELDEHS
APSEAVDLARLATSAAEALRPLASPRGMDLEVTLADGLPPVTGQSDQLAQLLQNLMENAV
KYGNDGTTVEVSVTLAGDLPAGAGAALRAGPVVKLAVKDHGEGIAAEHLPRLTERFYRVD
TARSRKMGGTGLGLAIVKHIVSHHRGLLAIDSRPGEGSTFTVWLPAAPA