Protein Info for AMB_RS00740 in Magnetospirillum magneticum AMB-1

Annotation: D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 182 TIGR01662: HAD hydrolase, family IIIA" amino acids 4 to 146 (143 residues), 121.8 bits, see alignment E=2.3e-39 TIGR01656: histidinol-phosphate phosphatase domain" amino acids 5 to 143 (139 residues), 150.4 bits, see alignment E=3.5e-48 PF00702: Hydrolase" amino acids 18 to 138 (121 residues), 38.3 bits, see alignment E=3.8e-13 PF08645: PNK3P" amino acids 22 to 126 (105 residues), 22.3 bits, see alignment E=1.9e-08 PF13419: HAD_2" amino acids 94 to 144 (51 residues), 26.3 bits, see alignment E=1.5e-09 PF13242: Hydrolase_like" amino acids 99 to 168 (70 residues), 59.6 bits, see alignment E=4.5e-20

Best Hits

Swiss-Prot: 39% identical to GMHBB_HAEDU: D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase (gmhB) from Haemophilus ducreyi (strain 35000HP / ATCC 700724)

KEGG orthology group: None (inferred from 100% identity to mag:amb0146)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2WB25 at UniProt or InterPro

Protein Sequence (182 amino acids)

>AMB_RS00740 D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase (Magnetospirillum magneticum AMB-1)
MKRFVLIDRDGTINVEKHYLSDPDQLELYPGVGRAIRRLNRLGLGVAVVTNQSGIARGYF
DLERLDQIHDRLYTLLEAEGAMVDGLYLCPHGPADDCTCRKPLPGMVEQAVADHHFDPAQ
AFMIGDKEVDVELGHAVGAVSILVRTGHGPKFVEGTKADHVVDDLPQAVAVIEKLLACAS
SS