Protein Info for ABZR88_RS20580 in Mucilaginibacter yixingensis YX-36 DSM 26809

Annotation: proline iminopeptidase-family hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 339 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details TIGR01250: proline-specific peptidase" amino acids 41 to 326 (286 residues), 294.9 bits, see alignment E=3.8e-92 PF12697: Abhydrolase_6" amino acids 64 to 314 (251 residues), 53.5 bits, see alignment E=8.3e-18 PF00561: Abhydrolase_1" amino acids 64 to 314 (251 residues), 93.4 bits, see alignment E=2.7e-30 PF12146: Hydrolase_4" amino acids 69 to 171 (103 residues), 41.7 bits, see alignment E=1.3e-14

Best Hits

Swiss-Prot: 46% identical to PIP_CHIPD: Proline iminopeptidase (Cpin_0261) from Chitinophaga pinensis (strain ATCC 43595 / DSM 2588 / NCIB 11800 / UQM 2034)

KEGG orthology group: K01259, proline iminopeptidase [EC: 3.4.11.5] (inferred from 52% identity to tsa:AciPR4_0927)

Predicted SEED Role

"Proline iminopeptidase (EC 3.4.11.5)" in subsystem Proline, 4-hydroxyproline uptake and utilization (EC 3.4.11.5)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.11.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (339 amino acids)

>ABZR88_RS20580 proline iminopeptidase-family hydrolase (Mucilaginibacter yixingensis YX-36 DSM 26809)
MKPHVLLLSAALCFAACKQNPSTNTPSTADTSSHEVKTGGSKLIKVDGKYNIYTKKVGDG
KIKVLLLNGGPGLPHDYMECFEDFLPKAGIEFYYYDQLGCGNSDTPKDTTLWIVPRYVEE
VEQVRKGLGLDSFYIVGHSWGSMLAMEYLHKYQSHVKGAVLSDMTAGVKEYVAYAEQLKK
KYFTPRDIVVFDSLSRLKKYDSEQYNTLLMTKLYANVLCRIPLEKWPEPLLRTFKKMNQP
IYMQMQGPDEFQITGNFKNWEFWSRLPDIKTPILVLGAKYDEMNPEDLKREGKLLPNSRT
YICPNGSHMAMYDDQQHYFGNLIAFLKDVDAGSFKPDAK