Protein Info for ABZR88_RS13880 in Mucilaginibacter yixingensis YX-36 DSM 26809

Annotation: membrane protein insertase YidC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 612 transmembrane" amino acids 6 to 24 (19 residues), see Phobius details amino acids 366 to 388 (23 residues), see Phobius details amino acids 433 to 455 (23 residues), see Phobius details amino acids 491 to 510 (20 residues), see Phobius details amino acids 522 to 538 (17 residues), see Phobius details amino acids 544 to 560 (17 residues), see Phobius details TIGR03593: membrane protein insertase, YidC/Oxa1 family, N-terminal domain" amino acids 3 to 343 (341 residues), 104 bits, see alignment E=1.3e-33 PF14849: YidC_periplas" amino acids 86 to 344 (259 residues), 102.7 bits, see alignment E=3.5e-33 TIGR03592: membrane protein insertase, YidC/Oxa1 family" amino acids 367 to 561 (195 residues), 186.7 bits, see alignment E=4.5e-59 PF02096: 60KD_IMP" amino acids 368 to 561 (194 residues), 179.8 bits, see alignment E=4.3e-57

Best Hits

Swiss-Prot: 42% identical to YIDC_PARD8: Membrane protein insertase YidC (yidC) from Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152)

KEGG orthology group: K03217, preprotein translocase subunit YidC (inferred from 60% identity to shg:Sph21_3520)

Predicted SEED Role

"Inner membrane protein translocase component YidC, long form"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (612 amino acids)

>ABZR88_RS13880 membrane protein insertase YidC (Mucilaginibacter yixingensis YX-36 DSM 26809)
MDKNTYTGFFMILVILVGFSFWMNHTNKEELAKQHKQHTIDSLNRIDSLKQAKLAVKVAP
GEKPVIDSAVLKSPFGAATMGSEQLVTLENADLRVKLSTRGGKVYSVELKNYKTFDKKPL
ILFDGSSNHFGLNLNAAGKSINTDKLYFTPSAPSLTVNGKDSSSLTMRLSYSPTQYIDYI
YSLKGEGNKLELSIKPTGLDDVVASTNSVNLQWTATLRKQEKDMKLERQYSTVYFKNSDN
DVDYLSVGKDDNKTINDKKLQWFSFKQHFFSNVLISKAGMSNANLSVAINPNDTANVKSM
TASVTLNKDNSGAVPMEFYFGPNRFKTLQAQGYDLEKQVDLGWGPLKYINRFATLPVFNV
LSSFNWNYGLIILALTVILKLVLSPLTYKSYLSMAKMRVLKPEMDEIKAKVGEDNPTLLQ
QEYMKLYKKAGVNPLGGCLPMLLQMPIVIAFFRFFPSLFELRGQSFLWMHDLSTYDSVIK
FGTSLPFLGDHISLMCLLMTISTLIYTYFNNQISGATGQMKYIGYVTPIIFLGALNGYPA
GLNYYYFLANMFTFLQQFLIRQMVDDKKIHAQIQENKKKPEDATKKKKSGFQARMEEMMR
QQQQAQQAKGKK