Protein Info for ABZR88_RS10710 in Mucilaginibacter yixingensis YX-36 DSM 26809

Annotation: TlpA disulfide reductase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 645 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF00578: AhpC-TSA" amino acids 482 to 608 (127 residues), 81.9 bits, see alignment E=9.9e-27 PF08534: Redoxin" amino acids 483 to 614 (132 residues), 76 bits, see alignment E=7.1e-25 PF13098: Thioredoxin_2" amino acids 504 to 614 (111 residues), 28.8 bits, see alignment E=3.3e-10 PF00085: Thioredoxin" amino acids 505 to 552 (48 residues), 38.6 bits, see alignment 2.3e-13 PF13905: Thioredoxin_8" amino acids 505 to 606 (102 residues), 52.9 bits, see alignment E=9.7e-18

Best Hits

Predicted SEED Role

"Thiol:disulfide oxidoreductase related to ResA" in subsystem Biogenesis of c-type cytochromes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (645 amino acids)

>ABZR88_RS10710 TlpA disulfide reductase family protein (Mucilaginibacter yixingensis YX-36 DSM 26809)
MKKITLLLILPFLMAKTVHAQNEHLKLSADQPSAGSTVGFTYNPDGTILAGKKKVEAAVY
YMDFKDSPADDVVLTADGNGVKGSLNIPSTAKAFFLSFAAGKIDDNNSQGYFYFIYENGK
PVEGAYGAKALWCSSSLSAYSGIKSSNIPEAIKLYEKEFELYPQSKAEFSSNYIMALSTS
GNDQYKAKADALVNEMAKSGDEKQMQVAMSIFMRQQKKAQVDSLASILKTKMLANLSVKG
KKAAAIDQEKDLAKKELLIDDFAKSFPDDLSAKLSMVDYWRGQTAKAYLNGGKLGDFERV
YAAINNKATLAGFFNNFAYDNAKQGKDLELDARICKLALDLAQKDVDNPAPRPFKTPKDT
KHYVEGVYGTYADSYAYILIKQGKYLEAYNYDQPVYEKNKGNIQIVETYVDILMGLNKYQ
EVLATIEIILKRGAATAKMDKDLKIAYVKTKGSDAGFDDYYAGFKNATDIKLRASLSKEM
MKQPAPGFTLKDLDGKTVSLADMKGKVVIVDFWATWCGPCKSSFPGMQMAVNKFKDNPNV
KFVFIDTWEHAENYIDGVKDFIAQTKYPFHVLLDEKGEDGRQSKVVSAYGVNGIPTKFII
DGNGNIRFKHVGFAGSDKGILDEVSAMIDIAMQTDVKTDNKAGEE