Protein Info for ABZR88_RS10085 in Mucilaginibacter yixingensis YX-36 DSM 26809

Annotation: M56 family metallopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 581 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 33 to 52 (20 residues), see Phobius details amino acids 90 to 115 (26 residues), see Phobius details amino acids 265 to 284 (20 residues), see Phobius details PF05569: Peptidase_M56" amino acids 146 to 255 (110 residues), 47.2 bits, see alignment E=1.7e-16

Best Hits

Predicted SEED Role

"Regulatory sensor-transducer, BlaR1/MecR1 family / TonB-dependent receptor" in subsystem Iron acquisition in Vibrio or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (581 amino acids)

>ABZR88_RS10085 M56 family metallopeptidase (Mucilaginibacter yixingensis YX-36 DSM 26809)
MPELFIYLIKVNVALLVFCAGYYLVLRRLTFYTLNRIYLVTAILFATLYSRVDLNNFLQR
HEQINKPIQVVIINWQAPVKALTTRHDQWYWLQMAFWAGVIILGMRLGTQLLSLYRLHKR
SEPLRIQQYFVRAIKGNVNPFSFWRSIYVNPENHEPNDLQAILEHEQIHVNEWHTLDILL
GELSAVFYWFNPGIWLMKRAIRENIEFITDRKILQKGMDTKTYQYSLLNVNLQAQNHAIA
NNFNISTIKKRIMMMNARRSSNINITRYLILVPAVMLMLLVFSVSKAEISRSLDKAGKVV
AKALNKAVVNLKEVLPEHAKIKADEPVAKPAKTIKAPPISINEAEQPEQLLTATYTTAVG
DTILKKQNIEYYINGKKVENLELNKIPAADIDHIEVYKDPKVSQAKGMVYITLKNANGTV
DTSKKANTFSIGTGKKSLDPVTVLGYRAAKKVKTDSAKVEELYQLRQSYNLTADTIHVTS
VKINGKKTGINTKANVIYLDSVSPKHTVTKLNNVQYADLPIFNQLNFDNKLIIINGKEAT
QKQFRKLSAADIKTVSKLSTAGAKAIYGDKGANGAIIITTK