Protein Info for ABZR88_RS09075 in Mucilaginibacter yixingensis YX-36 DSM 26809

Annotation: non-ribosomal peptide synthetase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1345 transmembrane" amino acids 1085 to 1104 (20 residues), see Phobius details amino acids 1199 to 1218 (20 residues), see Phobius details PF00668: Condensation" amino acids 48 to 462 (415 residues), 273.8 bits, see alignment E=6.2e-85 PF00501: AMP-binding" amino acids 494 to 834 (341 residues), 317.6 bits, see alignment E=2.7e-98 TIGR01733: amino acid adenylation domain" amino acids 513 to 909 (397 residues), 444.3 bits, see alignment E=2e-137 PF13193: AMP-binding_C" amino acids 893 to 971 (79 residues), 36.6 bits, see alignment 1.8e-12 PF00550: PP-binding" amino acids 999 to 1060 (62 residues), 51.6 bits, see alignment 2.3e-17 PF00975: Thioesterase" amino acids 1085 to 1331 (247 residues), 88.5 bits, see alignment E=1.9e-28

Best Hits

Predicted SEED Role

"Malonyl CoA-acyl carrier protein transacylase (EC 2.3.1.39)" in subsystem Fatty Acid Biosynthesis FASII or mycolic acid synthesis (EC 2.3.1.39)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.39

Use Curated BLAST to search for 2.3.1.39

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1345 amino acids)

>ABZR88_RS09075 non-ribosomal peptide synthetase (Mucilaginibacter yixingensis YX-36 DSM 26809)
MSLLTEEPVYKLKPVEFDPFAGPELLLIAPATEPQIEIWLSCKIGGVEASCAFNESFSLT
LTGSFNVAAFENAVHSLIDRHESLRALFSPDGTRMCIYRYLQPAYHFEDISGKDEKGQEQ
AIKDYLYRNSQTAFDLVFGPLFRVKLFKRTAERHHLTLTLHHIICDGWSFGVILQELGNL
YSAHAMGLTPNLPPAPKFSSYAAEQVDFQESATYADAEKFWLEQYQTRPPVLNLPSDQER
PSLRTYTSGHYHSSIDETLAAAVKKLGFAAGASVLTTLLAAFEVFMQQQTGCNDVVVGVP
SAGQPAIGLQGLVGHCVNLLPIRSFEPDDICFIDYLKRRRGEILDVYDHQLITFGGLLKK
LNLPRDPSRVPLVPVVFNSDMGMDSGISFHGIKHELKSNARRSENFEIFINLNDIGKGLN
IEWSYNAQLFNQAGIEKLATNFEVLLRTFTTDPRAHIKTSGLPAEPVKIDTITQWNKTET
WYPKEKPLHTLISEIAAKYDDKPAVVAGSVRISYRQLDERSNQLTRLLVDRGISKGDIVG
LAVERSVEMIITLLAIMKAGGTYVPIDPEYPADRIAYMLEDSSAKMLIVSERIQEQINSP
AQVLTLESALKQSASKMSTPVEVDVKGTDIAYVLYTSGSTGKPKGVQIAHYNLVNFLVGM
QAQPGIAADDKLLAVTTISFDIAGLEMYLPLVTGATVYIASADEARDGRRLLEIVKAEGI
TLMQATPYSWKMMLEAGWDNRLQLKALCGGEPLPKELAARLLPKCKALWNMYGPTETTIW
STVKEITLEDGDITIGKPIANTQVYILDEKLNILPAGVTGEIFIAGDGVSPGYLHRPELT
ADRFVIDPFTATTGSKMYRTGDLGKYLPNGELLCLGRVDFQVKIRGYRIEVQEIEHNLHQ
INEIKDAVVDARKDASGNLALVAYVVSQQFLPDTRTAIQNWRNALRENLPEYMVPQYFMV
VEEFPLTPNGKINRKALPEPDHNQARMAYAAPRTSIEQLVADIWRRYLGIEKIGIYDDFF
ELGGHSLIAVEIMTALQKETGKNLPLASLFQHSTIEQLALLLKIDGKSVSWDSLVPIKPV
GSKMPLYIVHGAGLNVLLFNTLAMNMDSDQPVYGLQARGLNGIDEPYDKMEDIAGHYVNE
IIAQNPNGPYALAGYSFGGIIAYEMAKQLEARGKQVKLLAMFDTYAYRSDYYDLWLKKYF
NRIRFFIMQILHSFVLLAKSPKRTIEYKSEMIRRRIVTFKRKFQGADGPKEGFSGYSHKI
DEANELAERNYKLAPYPIRVELFRAQKITFYMDDFENLGWKPYALKGVSIHEIPGEHNYI
FAPPNDKAFARILQDCLNKASSATA