Protein Info for ABZR88_RS07210 in Mucilaginibacter yixingensis YX-36 DSM 26809

Annotation: alpha-galactosidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 720 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF16875: Glyco_hydro_36N" amino acids 54 to 268 (215 residues), 182.5 bits, see alignment E=1.6e-57 PF02065: Melibiase" amino acids 272 to 613 (342 residues), 358.8 bits, see alignment E=4.3e-111 PF16874: Glyco_hydro_36C" amino acids 627 to 716 (90 residues), 63 bits, see alignment E=4.4e-21

Best Hits

KEGG orthology group: K07407, alpha-galactosidase [EC: 3.2.1.22] (inferred from 62% identity to phe:Phep_1706)

Predicted SEED Role

"Alpha-galactosidase (EC 3.2.1.22)" in subsystem Fructooligosaccharides(FOS) and Raffinose Utilization or Galactosylceramide and Sulfatide metabolism or Lactose and Galactose Uptake and Utilization or Melibiose Utilization (EC 3.2.1.22)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.22

Use Curated BLAST to search for 3.2.1.22

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (720 amino acids)

>ABZR88_RS07210 alpha-galactosidase (Mucilaginibacter yixingensis YX-36 DSM 26809)
MKYKKYILLPALALLTTGLHAQDGKRIAIETDHTALILNIGKNGRVYQSYLGERLADAAD
NNVLPQGKEAYITGGMEDQFQPAIRITHTDGNPSLELIYADKKVIHPDTGSTETIISLKD
PQYPITVNLHYQAYAHEDVIKAWTEIVNGEKGTIILNDYASSMLHFDAGSYWLTQFHGDW
AYEMQMQESKLTSGIKEIDSKLGTRADMYQSPMFLLSLNKLSDETSGEVMAGTLAWTGNF
RFHFEQDQNNSLRVVSGINPYASAYQLAAGKTFTTPAFIFSYSAHGRGQVSRNLHAWARN
YDVMDGNKSRLVLLNNWETTTFNFNEQRLDGIMDDAVKLGADLFLLDDGWFGNKYPRSND
KAGLGDWQETKTKLPNGITHLVKQADAKGTKFGIWIEPEMVNPKSELYEKHPDWIIKLPN
RAENYYRNQLVLDLANPKVADFVFNTMDDLIGKHPGLAFIKWDCNRLMSNNWSPYLKDKQ
SNLYVDYVLNLYDVLKRLRAKYPHLPIMLCSGGGARTDYEALKYFTEFWASDDTDPLERV
YIQWGYSNFFPSNTVTCHVTSWGKQSLKFRTDVAMMGKLGYDIDVSKMTPDELAFSQQAI
KNYKRLSSVIWFGELYRLVSPYEANRAVLMYVDGIKAKAVLFNYNLNIREREQVNRVRLQ
GLDPQKKYKVEEVNMMPGAKPILADNGRTYTGDYLMKIGLDLNGWHLKALTSSVVEMTAQ