Protein Info for ABZR88_RS06345 in Mucilaginibacter yixingensis YX-36 DSM 26809

Annotation: diaminopimelate decarboxylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02784: Orn_Arg_deC_N
  • amino acids 63 to 309 (247 residues), 101 bits, E=7.1e-33
• PF00278: Orn_DAP_Arg_deC
  • amino acids 310 to 399 (90 residues), 48.9 bits, E=6.3e-17

Best Hits

KEGG orthology group: K01586, diaminopimelate decarboxylase [EC: 4.1.1.20] (inferred from 60% identity to cts:Ctha_1896)

Predicted SEED Role

"Diaminopimelate decarboxylase (EC 4.1.1.20)" in subsystem Lysine Biosynthesis DAP Pathway (EC 4.1.1.20)

MetaCyc Pathways

• aspartate superpathway (21/25 steps found)
• superpathway of L-lysine, L-threonine and L-methionine biosynthesis II (13/15 steps found)
• superpathway of L-lysine, L-threonine and L-methionine biosynthesis I (14/18 steps found)
• L-lysine biosynthesis III (6/7 steps found)
• L-lysine biosynthesis VI (6/7 steps found)
• L-lysine biosynthesis I (7/9 steps found)
• L-lysine biosynthesis II (7/9 steps found)

KEGG Metabolic Maps

• Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
• Lysine biosynthesis

Isozymes

Compare fitness of predicted isozymes for: 4.1.1.20

Use Curated BLAST to search for 4.1.1.20

Protein Sequence (461 amino acids)

>ABZR88_RS06345 diaminopimelate decarboxylase (Mucilaginibacter yixingensis YX-36 DSM 26809)
MAKLKYERPVIKKMNAGLMNKFGTRTEFQPVRAIDGVPVLSLIEGYGSPLFVLSERQIRR
NYQSAARSFKTRYPKVQFAWSYKTNYLNAVCQIFHQEGSWAEVVSGFEYRKALGNGVAGN
QIIFNGPDKHRNDLLLAIENDSLIHIDNFDELYSLIELCNQINKKPRVAIRVNMDTGVYP
LWDRFGFNYENGQAWNAISKIVASGKMQLVGLHCHIGTFMLTTSAYMAAATKMCELATRC
KNLLHNPVEYLDLGGGFPSTNTLRGAYLPGVDTVPSIDDFAEAITTTILEYGFKQEELPL
LILETGRALIDDAGYLLGSVVANKRLSDGRRATIVNFGVNTLFTAFWYEHKITPAQDFTE
HTEDMVLYGPLCMNIDVVRENISLPLLNPGDHVVVHKVGAYNMTQWMQFITTRPAVVMID
EQQQVHLVRQAENLEYIEQMEQVPAHLNSHSLDAPSKERNF