Protein Info for ABZR88_RS06185 in Mucilaginibacter yixingensis YX-36 DSM 26809
Annotation: bifunctional aldolase/short-chain dehydrogenase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 88% identity to psn:Pedsa_3768)Predicted SEED Role
"Predicted rhamnulose-1-phosphate aldolase (EC 4.1.2.19) / Predicted lactaldehyde dehydrogenase (EC 1.2.1.22)" in subsystem L-rhamnose utilization (EC 1.2.1.22, EC 4.1.2.19)
MetaCyc Pathways
- L-rhamnose degradation I (5/5 steps found)
- L-lactaldehyde degradation (aerobic) (1/2 steps found)
- methylglyoxal degradation IV (1/3 steps found)
- methylglyoxal degradation V (1/3 steps found)
- lactate biosynthesis (archaea) (2/5 steps found)
- superpathway of fucose and rhamnose degradation (7/12 steps found)
- superpathway of methylglyoxal degradation (3/8 steps found)
- L-rhamnose degradation II (2/8 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 1.2.1.22
Use Curated BLAST to search for 1.2.1.22 or 4.1.2.19
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (706 amino acids)
>ABZR88_RS06185 bifunctional aldolase/short-chain dehydrogenase (Mucilaginibacter yixingensis YX-36 DSM 26809) MSVNTIDFKHVSYLWDDAKAAEMAGDEVALLIYRSNLLGADLRLTNYGGGNTSCKAMAKD PLTGEEVEVMWVKGSGGDLGSIKRNGLAALYVDRLRALKNIYRGIEHEDEMVELFNHCIY DLASKAPSIDTPLHGFLPFAHIDHLHPDAAIAIAAAKDGKKITQELFGGTIGWVEWQKPG FDLGLQLKACLDENPGIRGIMLGSHGLFTWGDTAYESYINTLEVIEKCAEYLEQNYGKKG PIFGGQKIESLAAEDRKKQAVALAPVLRGFCSSKTRMIGHFTDDARVLEYTNSNDLERLA PLGTSCPDHFLRTKISPLVLELAPNEDLSDVDALKAKLLPAFEAYRAMYEDYYNTCKHPN SPAIRDANPVVILYPGVGMFTFAKDKQTARVAAEFYINAINVMKGAEAISEYTSLPRQEA FNIEYWLLEEAKLQRMPKPKALSGRIALVTGSAGGIGKAIAKKFAEEGAVVVLNDMNAER LEGAGEEFKAKFGKDAYATAVLDVTNGAQINEAVAEAILAFGGVDLIVNNAGLSISKTIA DHTEKDWDLLYDVLVKGQFLVTQAAVAVMKKQDIGGDIINIVSKNALVSGPNNAGYGSAK AAQLHLSRLNAAELGGDKIRVNVVNPDAVISDSNIWAGGWAEGRAKAYGITVAELPAYYA KRTLLNEIILPDDIANACFAITGGLLNKSTGNVVNVDGGVAAGFVR