Protein Info for ABZR88_RS04820 in Mucilaginibacter yixingensis YX-36 DSM 26809

Annotation: ATP-dependent Clp protease ATP-binding subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 849 PF02861: Clp_N" amino acids 17 to 67 (51 residues), 64.1 bits, see alignment 8.1e-21 amino acids 96 to 144 (49 residues), 40.3 bits, see alignment 2.2e-13 PF00004: AAA" amino acids 226 to 338 (113 residues), 44.7 bits, see alignment E=1.4e-14 amino acids 563 to 680 (118 residues), 32.8 bits, see alignment E=6.7e-11 PF07728: AAA_5" amino acids 226 to 304 (79 residues), 23.2 bits, see alignment E=4.6e-08 amino acids 562 to 687 (126 residues), 51.4 bits, see alignment E=8.8e-17 PF17871: AAA_lid_9" amino acids 364 to 466 (103 residues), 112.9 bits, see alignment E=4.8e-36 PF02151: UVR" amino acids 438 to 470 (33 residues), 24.7 bits, see alignment (E = 1.1e-08) PF00158: Sigma54_activat" amino acids 532 to 671 (140 residues), 32.9 bits, see alignment E=3.8e-11 PF07724: AAA_2" amino acids 557 to 730 (174 residues), 227 bits, see alignment E=1e-70 PF10431: ClpB_D2-small" amino acids 737 to 817 (81 residues), 87.4 bits, see alignment E=4e-28

Best Hits

KEGG orthology group: K03696, ATP-dependent Clp protease ATP-binding subunit ClpC (inferred from 68% identity to cts:Ctha_0300)

Predicted SEED Role

"ATP-dependent Clp protease ATP-binding subunit ClpA" in subsystem Proteolysis in bacteria, ATP-dependent

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (849 amino acids)

>ABZR88_RS04820 ATP-dependent Clp protease ATP-binding subunit (Mucilaginibacter yixingensis YX-36 DSM 26809)
MEAKFSPRVKDVISYSREEALRLGHDYIGTEHLLLGLIRDGDGVAIKLLKGLNVDTARLR
RAVEDAVKGTTGTNVHIGSIPLTKQAEKVLKITYLEAKIFKSDVIGTEHLLLSILRDEDN
IASQLLLQFNVNYDIFKQEVDAQRNGITDEMPGSSTGGDDDFKEEESFSQPKKVSDIKSK
TPVLDNFGRDLTKAAEEGRLDPIVGREKEIERVSQILSRRKKNNPILIGEPGVGKSAIAE
GLALRIVQRKVSRVLFNKRVVTLDLASLVAGTKYRGQFEERMKAVMNELEKSPDVILFID
EIHTIVGAGGASGSLDASNMFKPALARGEIQCIGATTLDEYRQYIEKDGALDRRFQKVMV
EPASPEETIEILNRIKEKYEEHHGVTYTPEAINACVTLTTRYITDRFLPDKAIDALDESG
SRVHLTNIHVPQDILDIEQKIEQIKIEKNKVVRSQKYEEAAKLRDTEKHLLEELEQAKAV
WEAETKSKRYTVTEDNVAEVVAMMTGIPVQKVGQADSQKLLHMSENIQGKIIGQEDAIKK
LTKAIQRTRAGLKDPKKPIGSFIFLGPTGVGKTELAKELARFMFDSEDALIQIDMSEYME
KFAVSRLVGAPPGYVGYEEGGQLTEKVRRKPYAVVLLDEIEKAHPDVFNILLQVLDEGQL
TDSLGRKVDFRNAIIIMTSNIGARQLKDFGQGVGFSTSAKNTQADAHSRGVIENALKRAF
APEFLNRIDDVIVFNSLSKEDIFKIIDIELSALFGRVNTLGYKIELTLNAKEFIAEKGYD
SQFGARPLKRAIQKYLEDPIAEEILKGELVEGDTMEVDYDKETSEIKINVKSSGESAVSD
TKPNDGPLN