Protein Info for ABZR88_RS01125 in Mucilaginibacter yixingensis YX-36 DSM 26809

Annotation: glycoside hydrolase family 2 TIM barrel-domain containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1098 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF02837: Glyco_hydro_2_N" amino acids 80 to 246 (167 residues), 152 bits, see alignment E=3.9e-48 PF00703: Glyco_hydro_2" amino acids 249 to 369 (121 residues), 54.1 bits, see alignment E=6.4e-18 PF02836: Glyco_hydro_2_C" amino acids 376 to 680 (305 residues), 266.1 bits, see alignment E=9.7e-83 PF16353: LacZ_4" amino acids 691 to 780 (90 residues), 59.2 bits, see alignment E=9.8e-20 PF02929: Bgal_small_N" amino acids 810 to 1078 (269 residues), 246.3 bits, see alignment E=1e-76

Best Hits

Predicted SEED Role

"Beta-galactosidase (EC 3.2.1.23)" in subsystem Galactosylceramide and Sulfatide metabolism or Lactose and Galactose Uptake and Utilization or Lactose utilization (EC 3.2.1.23)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.23

Use Curated BLAST to search for 3.2.1.23

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1098 amino acids)

>ABZR88_RS01125 glycoside hydrolase family 2 TIM barrel-domain containing protein (Mucilaginibacter yixingensis YX-36 DSM 26809)
MRKQLAIITSLLLSGSAYAQLVDKTPAAIPNAPSVYNAEPWENPQVDGINRDEARATAYS
YPNVQEALVGDRTKSGRWLSLNGMWDFNYAAKPADAPQDFYKGRVSGWKKIPVPSSIEMQ
GYDKPIYKSAVYPFRPVNPPHVPQDYNGMGSYQRTFTVPADWKDMNITLHFGGVSSGFKV
WVNGKFLGYGEDSFMPSEFNVTPYLQAGENILSVQLIRWSDGYFLEDQDQWRMSGIHREV
MLMAEPKLRIADFQWEGKLDKEYKDVRFMIRTRMENLTGKAVPGYHLEAQLYDKNNKPVF
AKPLNRSVESIINEIYPRLDNVKFAQLEAQVKNPDKWSDEHPNLYTLALSLIDTTGKTVE
VKSCKVGFRSIEFSKTDSKLLINGKVTYLYGVNRPDHDPVKGKALSREDILRDVQTIKKF
NFNCIRTSHYPMDPYLYDLCDQYGILVIDEANLETHGLGSKLSNDPMWTGAYLDRVTRMV
ERDKNHPSIIVWSLGNEAGRGPNHAAMAGWVHDFDITRPVHYEPAQGTPQAEGYIEPGDP
RYPKTNDHSHRLQNPIDQPYTDFISRMYPGLYTAPLLANQQNGDHRPIFFVEYSHAMGNS
NGNLKEFWDQWRTTPRVIGGAIWEFKDQGLLKKDSTGKSYYAYGGDYGERYYDDFTIKGI
VDPAGRPKPAIYECKHVFQPAECTLKDGANIHIKNWSSVANLNEYEVYLQVREDGQVISK
KIMPRVNLAAGHDTTISIKSYLPSFKAGHEYLADIHFALAEDKAWEKKGYEIAEDQFALT
SLAEVKPVAKTYPALKVEDIGNFAMTGIKNGNVSISFDKKSGLLIGYAVKGQQQIISPPM
PHFVRPVTDNDHRGWKMERKLKAWFNAQLKVKSVNIDKSQADNGIVKITDVYSVIPDSAS
VTLVYTINGDGAIKVDYNLQANTKLPNLPKVGLQMGIDKADTTITYYGRGPWENYIDRNT
GSEAGVYTSTISNFMEPYVIPQENGNRTDVRWMLLADKQNKGLLVVADSLLSMSAWPYTE
DNIVKAKHTNKLRDGGQVTLNIDLKQMGVGGNDSWSEVAEALEKYRIPAGNYHYSFYLMP
YSGKPEDAGAAALKLKTR