Protein Info for ABZR88_RS00765 in Mucilaginibacter yixingensis YX-36 DSM 26809
Annotation: alkaline phosphatase family protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 49% identity to cly:Celly_0896)Predicted SEED Role
"Alkaline phosphodiesterase I (EC 3.1.4.1) / Nucleotide pyrophosphatase (EC 3.6.1.9)" in subsystem Purine conversions (EC 3.1.4.1, EC 3.6.1.9)
MetaCyc Pathways
- superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (17/18 steps found)
- pyrimidine deoxyribonucleotides de novo biosynthesis I (9/9 steps found)
- superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) (12/14 steps found)
- pyrimidine deoxyribonucleotides de novo biosynthesis III (8/9 steps found)
- dZTP biosynthesis (4/5 steps found)
- pyrimidine deoxyribonucleotides de novo biosynthesis II (5/7 steps found)
- pyrimidine deoxyribonucleotides dephosphorylation (2/3 steps found)
- tunicamycin biosynthesis (2/9 steps found)
KEGG Metabolic Maps
- Nicotinate and nicotinamide metabolism
- Pantothenate and CoA biosynthesis
- Purine metabolism
- Riboflavin metabolism
- Starch and sucrose metabolism
Isozymes
Compare fitness of predicted isozymes for: 3.1.4.1, 3.6.1.9
Use Curated BLAST to search for 3.1.4.1 or 3.6.1.9
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (451 amino acids)
>ABZR88_RS00765 alkaline phosphatase family protein (Mucilaginibacter yixingensis YX-36 DSM 26809) MKRFLRSVICCLLLSPAVMAQDKHVVLISVDGFRPEFYMDPAWGMVNVRQGMQKGTYAEG VRGSFPTVTYPSHTTIITGVLPAKHGIYYNTPVEPLGITGKWFWFYKDIKVPTLWTAAKD AGLTTAGVSWPVTVGAPIDYNLPEYVILPKGKGEKKDEIKAMYMESNPKSLFEEVQENAI GKFGEYGATLDFYNSDQNKARMAAYIIRKYKPAFLAVHIALTDHFEHEQGRDGDKVRSAV SGADAAIKTITDAIEMAGLAKNTTFIITGDHGFVDIHSQFNPNVMLAKAGLYDNDHKENW KAYFQASGGSAFLQLRDPKDKATLAKVNEALANLPDGVKKLFHVLDKKHVTEAQGDPNAA LALAAYRGVSFGATAAGELLTAAKGGTHGYLPTDFKDIQTGFVAYGRGIKPGVVLPQIGQ EDIAPLIAYLLDLKLATDGVLYPGVLAPAKK