Protein Info for ABIE41_RS24220 in Bosea sp. OAE506

Annotation: potassium-transporting ATPase subunit KdpB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 680 transmembrane" amino acids 36 to 54 (19 residues), see Phobius details amino acids 64 to 84 (21 residues), see Phobius details amino acids 222 to 245 (24 residues), see Phobius details amino acids 254 to 278 (25 residues), see Phobius details amino acids 585 to 606 (22 residues), see Phobius details amino acids 614 to 634 (21 residues), see Phobius details amino acids 652 to 674 (23 residues), see Phobius details TIGR01497: K+-transporting ATPase, B subunit" amino acids 11 to 674 (664 residues), 993.7 bits, see alignment E=3.6e-303 TIGR01494: HAD ATPase, P-type, family IC" amino acids 74 to 345 (272 residues), 105.9 bits, see alignment E=1.8e-34 amino acids 374 to 597 (224 residues), 152.4 bits, see alignment E=1.4e-48 PF00122: E1-E2_ATPase" amino acids 123 to 286 (164 residues), 103.1 bits, see alignment E=2.6e-33 PF00702: Hydrolase" amino acids 303 to 528 (226 residues), 93.9 bits, see alignment E=3.4e-30

Best Hits

Swiss-Prot: 63% identical to KDPB_DEIRA: Potassium-transporting ATPase ATP-binding subunit (kdpB) from Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)

KEGG orthology group: K01547, K+-transporting ATPase ATPase B chain [EC: 3.6.3.12] (inferred from 67% identity to rle:pRL110380)

Predicted SEED Role

"Potassium-transporting ATPase B chain (EC 3.6.3.12) (TC 3.A.3.7.1)" in subsystem Potassium homeostasis (EC 3.6.3.12, TC 3.A.3.7.1)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.12

Use Curated BLAST to search for 3.6.3.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (680 amino acids)

>ABIE41_RS24220 potassium-transporting ATPase subunit KdpB (Bosea sp. OAE506)
MSKHAPTEMGLFSPVILRPAILQAFRKLDPRSLARNPVIFSTALVSVLASVLVIREGLTG
GPVFWIGLQIAIWLWFTVLFANFAEAVAEGRGKARADAFRSTRSSSLAKVLVDPANRVVY
GTKEVELVEPGEVILIEAGDTVPTDGEIIEGVASVDESAITGESAPVIRESGGDRSSVTG
GTRLVSDWLVVRVTARQGETFLDRMIALVEGAKRQKTPNEIALDILLAALTLVFLFVVVT
LPFFASWSGTTLPVIYLAALFVTLIPTTIGGLLSAIGIAGMDRLVKANVIAKSGRAVEAA
GDIDVLLLDKTGTITFGNRMAHAFEPAANISERDLAEAAFLASLSDDTPEGKSIVDLAAK
RFGFDAAAGAGAVFVPFTAQTRMSGVDLPDGRALRKGASDTMAKLTGGTLSATVEQAVRK
IASSGGTPLVVARDNDVLGVVHLKDVVKPGIRERFAELRRMGIRTVMITGDNPLTAAAIA
AEAGVDDFLAEATPEAKLALIRKEQAEGRLVAMCGDGSNDAPALAQADVGVAMNSGTPAA
KEAGNLIDLDSDPTKLIEIVMVGKQLLISRGALTTFSIANDVAKYFAILPALFVTAYPGL
AVLDVMGLGSPQSAILSAIIFNALVIVALIPIALKGVRYAPASAASLLGRNLLVYGLGGL
IVPFIGIKAIDLIVDLLHLA