Protein Info for ABIE41_RS22950 in Bosea sp. OAE506

Annotation: cytochrome c oxidase subunit I

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 543 transmembrane" amino acids 37 to 58 (22 residues), see Phobius details amino acids 83 to 109 (27 residues), see Phobius details amino acids 122 to 140 (19 residues), see Phobius details amino acids 172 to 197 (26 residues), see Phobius details amino acids 209 to 236 (28 residues), see Phobius details amino acids 261 to 283 (23 residues), see Phobius details amino acids 292 to 315 (24 residues), see Phobius details amino acids 329 to 351 (23 residues), see Phobius details amino acids 363 to 384 (22 residues), see Phobius details amino acids 399 to 422 (24 residues), see Phobius details amino acids 434 to 455 (22 residues), see Phobius details amino acids 476 to 500 (25 residues), see Phobius details TIGR02891: cytochrome c oxidase, subunit I" amino acids 27 to 537 (511 residues), 714.8 bits, see alignment E=2.8e-219 PF00115: COX1" amino acids 35 to 485 (451 residues), 527.2 bits, see alignment E=1.7e-162

Best Hits

Swiss-Prot: 77% identical to COX1_BRADU: Cytochrome c oxidase subunit 1 (ctaD) from Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)

KEGG orthology group: K02274, cytochrome c oxidase subunit I [EC: 1.9.3.1] (inferred from 80% identity to mrd:Mrad2831_0032)

MetaCyc: 66% identical to complex IV subunit 1 (Arabidopsis thaliana col)
CYTOCHROME-C-OXIDASE-RXN [EC: 7.1.1.9]

Predicted SEED Role

"Cytochrome c oxidase polypeptide I (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1 or 7.1.1.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (543 amino acids)

>ABIE41_RS22950 cytochrome c oxidase subunit I (Bosea sp. OAE506)
MATAAPHAPAHGHHDDAHAHPTGWRRWLMSTNHKDIGTLYLIFSIMAGLVGGFLSIMMRI
ELQQPGLQIFANGQSYNVFVTGHGLIMIFFMVMPAVIGGFGNWFVPLMIGAPDMAFPRMN
NISFWLTVAAFVLLIMSMFMEGAPGAQGVGTGWTIYPPFSSSGHPGPAVDFGIFALHLAG
AASILGAINFITTILNMRAPGMTLHKMPLFAWGVLVTAFLLLLALPVLAGAITMLLTDRN
FGTTFYDPAGGGDPILYQHLFWFFGHPEVYIMILPAFGIVSHIISTFSKKPIFGYLGMAY
AMVAIGVVGFIVWAHHMYTAGLSLNTQRYFVFATMVIAVPTGIKIFSWIATMWGGSIRFT
APMIWAIGFIFLFTVGGVTGVVLANAGVDRSLHATYYVVAHFHYVLSLGAVFGIFAGFYY
WFPKMSGYVIPDWIGKLHFWVAFFGANLLFFPQHFLGLAGMPRHYVDYPDAFAGWHFWSS
IGSYIFAAGLLIFFYGVYVAFSRKELAGDNPWGEGATTLEWTLSSPPPFHQFETLPRISG
SDH