Protein Info for ABIE41_RS22810 in Bosea sp. OAE506

Annotation: molybdopterin cofactor-binding domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 704 PF20256: MoCoBD_2" amino acids 20 to 139 (120 residues), 73.2 bits, see alignment E=2.6e-24 amino acids 557 to 648 (92 residues), 51.8 bits, see alignment E=8.7e-18 PF02738: MoCoBD_1" amino acids 299 to 426 (128 residues), 58.6 bits, see alignment E=5.3e-20 amino acids 470 to 529 (60 residues), 30.3 bits, see alignment 2.3e-11

Best Hits

KEGG orthology group: None (inferred from 57% identity to bja:blr6047)

Predicted SEED Role

"Isoquinoline 1-oxidoreductase beta subunit (EC 1.3.99.16)" in subsystem N-heterocyclic aromatic compound degradation (EC 1.3.99.16)

Isozymes

Compare fitness of predicted isozymes for: 1.3.99.16

Use Curated BLAST to search for 1.3.99.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (704 amino acids)

>ABIE41_RS22810 molybdopterin cofactor-binding domain-containing protein (Bosea sp. OAE506)
MSAATVLPAGLRVTPRLDRWLAVSPEGHVTLSPGKVEIGQGILTALAQICADELDIAVER
VRLRPADTAASPNEGVTSGSLSVSDCGLSVRLAAAQTRGLFLAEAARLLSVPQEALSVED
GAITGPGNLATSYWELAGQVSLACPADPAVQPKAPGARTVTGRPVPRIDLAGKVFGTRPF
IHDLDQAGLLHGRVLRAPRPGATLESLDEAALAGLDGLVAWVRDGSFLGLVCESEVQAEA
ALVSLATAARWTGGFELPDQHDLSAWLQGEPAEASIVDLRDGPEPSPSTRRLVRRYLKPY
LAHASIGPSCAIATWAEDGLRVVTHSQGIFNLRADLALVFGLPEDAIIVTHAEGAGCYGH
NGADDAALDAALLARAVPGRPVRLRWSRADELARSPFGAAMAIEIAAEVGKDGRIAGWSH
EIWSNGYVARPGRAGSPALLASFDLEKPFPLYISQDPPLAGGGGAQRNAVPLYDFPSWRI
AKNRLLTMPLRTSSMRALGAFGNVFAIESMMDELAYEQGEDPLAFRLRHLGDARARTVLE
RAAAMADGGGPVLEGRGRGLAFARYKNTGAYCAVVAEIDLAAEPRATQLWIAVDVGEAIN
PDGVANQIEGGAVQATSWTLKEEVAFSREAVTSTSWETYPILRFSEVPEVTVEIVPRPDL
PPLGAGECAQGPTAAALANAVHAALGVRVRQMPITRDRIIAAME