Protein Info for ABIE41_RS21955 in Bosea sp. OAE506

Annotation: 3-oxo-tetronate kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 421 PF07005: SBD_N" amino acids 3 to 229 (227 residues), 253.1 bits, see alignment E=2.8e-79 PF17042: NBD_C" amino acids 257 to 413 (157 residues), 139.9 bits, see alignment E=1.2e-44

Best Hits

Swiss-Prot: 56% identical to OTNK_CUPNH: 3-oxo-tetronate kinase (otnK) from Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)

KEGG orthology group: None (inferred from 58% identity to bgd:bgla_2g06400)

MetaCyc: 56% identical to 3-dehydrotetronate 4-kinase monomer (Cupriavidus necator H16)
RXN-18594 [EC: 2.7.1.217]; 2.7.1.217 [EC: 2.7.1.217]

Predicted SEED Role

"FIG00641944: hypothetical protein"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.217

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (421 amino acids)

>ABIE41_RS21955 3-oxo-tetronate kinase (Bosea sp. OAE506)
MLLGVIADDMTGATDVALMLNRSGMRTVQTIGVPSPGQALPDADAVVVALKSRTNPVAEA
VADSLAACEALLAAGARQILFKYCSTFDSTAQGNIGPVAGALAQRLGAGLAIVCPAFPAN
GRSIYQGYLFVGAVPLHESSMKDHPLTPMRDSSLIRLMGAQTSGAVGLVDYATVLSGAGA
VKARFAALADQGMRYVVTDALTNADLMVLGEAAADHKLLTGGSGIAMGLPQNFRRAGLLP
EREIAASLAAPQGRAGIISGSCSTATRGQIAKAIEAGYPALKVDPMALVSGAQDAAKLAD
WALAQAADTPFLLYSSDDPAEVATIQEKLGRETAGETVEHAFAQTAALLAEGGVSRLLVA
GGETSGAVVQELGIGLLEIGPEIDPGVPWTRVAQGRDMVIALKSGNFGAPDFFLKAWALL
R