Protein Info for ABIE41_RS21155 in Bosea sp. OAE506

Annotation: multidrug effflux MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 396 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details transmembrane" amino acids 43 to 63 (21 residues), see Phobius details amino acids 75 to 93 (19 residues), see Phobius details amino acids 100 to 121 (22 residues), see Phobius details amino acids 133 to 151 (19 residues), see Phobius details amino acids 163 to 183 (21 residues), see Phobius details amino acids 211 to 236 (26 residues), see Phobius details amino acids 248 to 271 (24 residues), see Phobius details amino acids 278 to 298 (21 residues), see Phobius details amino acids 304 to 324 (21 residues), see Phobius details amino acids 340 to 363 (24 residues), see Phobius details amino acids 369 to 388 (20 residues), see Phobius details TIGR00710: drug resistance transporter, Bcr/CflA subfamily" amino acids 9 to 386 (378 residues), 232.5 bits, see alignment E=5.5e-73 PF07690: MFS_1" amino acids 16 to 347 (332 residues), 146 bits, see alignment E=2.9e-46 PF06609: TRI12" amino acids 26 to 178 (153 residues), 36.8 bits, see alignment E=3.4e-13 PF00083: Sugar_tr" amino acids 44 to 186 (143 residues), 47.7 bits, see alignment E=2.3e-16 PF13347: MFS_2" amino acids 130 to 320 (191 residues), 33.1 bits, see alignment E=4.9e-12

Best Hits

KEGG orthology group: K07552, MFS transporter, DHA1 family, bicyclomycin/chloramphenicol resistance protein (inferred from 35% identity to pmk:MDS_0923)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (396 amino acids)

>ABIE41_RS21155 multidrug effflux MFS transporter (Bosea sp. OAE506)
MNASALKPTLTVLVAMSALQPIALNLLAPAAPALSRHFGSSYATIQLALTFFLVAVALTQ
LVSGPLSDRFGRRPCVNAGIVLFIAGSVLGALAPSIEVLLLARVLEGAGSGSVFALSRAI
IRDTASRDEAASQIATVTMVMVVAPMIAPWLGGQIETALGWRMILWFMAASGVVTLMLTL
ARLPETAPNLGQRTPLLGVFRAFPELITNRVFVLNVVAVSTSSATFFAFIAAAPYIVVET
MGRGSDTYGAFFILNAAGYMVGNFAMARLVVKIGAPRMVRLGLVISSIAMTVAVPLSLSP
AWSPLMLFLPLAINSIGNGMTIPGSTAEALSARPELAGSAAGLMGAIQLGLSALMTVLIS
WLVTIWPPSLVVLMWVLTLTGLVAVYFGRRGTSPRR