Protein Info for ABIE41_RS20060 in Bosea sp. OAE506

Annotation: acyl-CoA dehydrogenase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 568 PF02771: Acyl-CoA_dh_N" amino acids 178 to 289 (112 residues), 119.5 bits, see alignment E=2e-38 PF02770: Acyl-CoA_dh_M" amino acids 295 to 395 (101 residues), 58.7 bits, see alignment E=1.1e-19 PF00441: Acyl-CoA_dh_1" amino acids 410 to 558 (149 residues), 139.8 bits, see alignment E=1.6e-44 PF08028: Acyl-CoA_dh_2" amino acids 427 to 546 (120 residues), 50.8 bits, see alignment E=4.2e-17

Best Hits

KEGG orthology group: K14448, (2S)-methylsuccinyl-CoA dehydrogenase (inferred from 75% identity to mrd:Mrad2831_4351)

Predicted SEED Role

"Methylsuccinyl-CoA dehydrogenase, predicted by (Erb et al, 2007)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (568 amino acids)

>ABIE41_RS20060 acyl-CoA dehydrogenase family protein (Bosea sp. OAE506)
MSAQAAAIHVAEPAPESATALIAAALPGFETLLQNAVAAVRAKVTVEGKISSARLEAQQH
AAHGLAWLATYVMSLREMKAYGERLASENRYGAIEDYAIRIGAGEYAAQIFGGIPMSQGE
IIRLAALGLSEKAIAAADTPAARALIAQGNTPENRARLVDLFSQDDGAAGVGDPGLDETL
EAIRSEMRRFCAAEVTPHAHEWHLKNDYIPMEVVEKMAELGVFGLTIPEEFGGMGLTKVS
MCVVSEELSRAYIGVGSLGTRSEIAAELILCGGTAEQKEQWLPKLASGEVLPTAVFTEPN
TGSDLASLRTRAVKDGDVWKVSGNKTWITHPVRADIMTLLVRTDPTESGYKGLSMLIAEK
PRGTDEDPFPVAGLTGGEIEVLGYRGMKEYELAFDGFTVKGENLLGGVEGQGFKQLMQTF
EAARIQTAARAVGVAQSAFDLGLRYARERVQFGKKLIAFPRVADKLAMMAAEILIARQLT
YFAAREKDAERRCDLEAGMAKLLGARVAWAAADNALQIHGGNGFALEYAISRVLCDARIL
NIFEGAAEIQAQVIARRLVEDADASRAA